An ORC/Cdc6/MCM2-7 Complex Is Formed in a Multistep Reaction to Serve as a Platform for MCM Double-Hexamer Assembly

Alejandra Fernandez‐Cid, Alberto Riera, Silvia Tognetti, +7

Molecular Cell

Supramolecular AssemblyMultistep ReactionNatural SciencesSelf-assemblyMolecular Self-assembly +7

A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2–7 onto DNA

Stefan A. Samel, Alejandra Fernandez‐Cid, Jingchuan Sun, +5

Genes & Development

Protein AssemblyClosed Ring StructureMolecular BiologyNucleic Acid ChemistryProtein Folding +16

Structural and mechanistic insights into Mcm2–7 double-hexamer assembly and function

Jingchuan Sun, Alejandra Fernandez‐Cid, Alberto Riera, +5

Genes & Development

The Fidelity of Synaptonemal Complex Assembly Is Regulated by a Signaling Mechanism that Controls Early Meiotic Progression

Nicola Silva, Nuria Ferrándiz, Consuelo Barroso, +10

Developmental Cell

ChromatinDevelopmental BiologyCell DivisionGeneticsMeiosis +10

Yeast Cip1 is activated by environmental stress to inhibit Cdk1–G1 cyclins via Mcm1 and Msn2/4

Ya-Lan Chang, Shun‐Fu Tseng, Yu‐Ching Huang, +12

Nature Communications

Human SIRT1 regulates DNA binding and stability of the Mcm10 DNA replication factor via deacetylation

Samuel Fatoba, Silvia Tognetti, Mélissa Berto, +5

Nucleic Acids Research

Molecular RegulationMolecular BiologyEpigeneticsDna Replication InitiationTranscriptional Regulation +14

The ORC/Cdc6/MCM2-7 complex facilitates MCM2-7 dimerization during prereplicative complex formation

Cécile Evrin, Alejandra Fernandez‐Cid, Alberto Riera, +6

Nucleic Acids Research

A Clb/Cdk1-mediated regulation of Fkh2 synchronizes CLB expression in the budding yeast cell cycle

Christian Linke, Anastasia Chasapi, Alberto González‐Novo, +8

npj Systems Biology and Applications

Hog1 activation delays mitotic exit via phosphorylation of Net1

Silvia Tognetti, Javier Jiménez, Matteo Viganò, +4

Proceedings of the National Academy of Sciences

ChromatinSignal TransductionCell RegulationCell DivisionCell Control +12

A reconstituted system reveals how activating and inhibitory interactions control DDK dependent assembly of the eukaryotic replicative helicase

M. Carmen Herrera, Silvia Tognetti, Alberto Riera, +4

Nucleic Acids Research