Concepedia

Proteostasis Network

Proteostasis Network is a biological regulatory framework that integrates molecular pathways and cellular mechanisms responsible for maintaining protein homeostasis by coordinating the synthesis, folding, trafficking, and degradation of proteins within a cell.

155

Publications

8.9K

Citations

1.1K

Authors

435

Institutions

Publications per year

2017–2026

97

Parents

Publications

155

A Chaperome Subnetwork Safeguards Proteostasis in Aging and Neurodegenerative Disease

Marc Brehme, Cindy Voisine, Thomas Rolland et al. · Cell Reports · 2014 · 607 citations · Full text

, , +17

Stress-Independent Activation of XBP1s and/or ATF6 Reveals Three Functionally Diverse ER Proteostasis Environments

Matthew D. Shoulders, Lisa M. Ryno, Joseph C. Genereux et al. · Cell Reports · 2013 · 583 citations · Full text

, , +15

The Mechanistic Links Between Proteasome Activity, Aging and Agerelated Diseases

Isabel Sáez, David Vı́lchez · Current Genomics · 2014 · 335 citations · Full text

, , +17

Dynamic control of Hsf1 during heat shock by a chaperone switch and phosphorylation

Xu Zheng, Joanna Krakowiak, Nikit Patel et al. · eLife · 2016 · 260 citations · Full text

, , +17

Distinct proteostasis circuits cooperate in nuclear and cytoplasmic protein quality control

Rahul S. Samant, Christine M. Livingston, Emily M. Sontag et al. · Nature · 2018 · 188 citations

, , +11

1–5 of 155

Authors

1.1K

  1. JW
    Jeffery W. Kelly

    Scripps Research Institute, United States

    11 publications · 1.1K citations

    11

    h-index

  2. RI
    Richard I. Morimoto

    Northwestern University, United States

    9 publications · 1K citations

    8

    h-index

  3. IP
    Ioannis P. Trougakos

    National and Kapodistrian University of Athens, Greece

    7 publications · 358 citations

    7

    h-index

  4. ET
    Evan T. Powers

    Scripps Research Institute, United States

    7 publications · 387 citations

    6

    h-index

  5. MD
    Matthew D. Shoulders

    Massachusetts Institute of Technology, United States

    5 publications · 757 citations

    5

    h-index

1–5 of 1.1K

Institutions

435

  1. Scripps Research Institute

    San Diego, United States

    18 h-index

    83 publications

    9.3K citations

  2. Harvard University

    Cambridge, United States

    11 h-index

    39 publications

    3.3K citations

  3. Northwestern University

    Evanston, United States

    10 h-index

    45 publications

    5.2K citations

  4. Rice Institute

    Hebron, United States

    8 h-index

    26 publications

    3.7K citations

  5. National and Kapodistrian University of Athens

    Athens, Greece

    7 h-index

    40 publications

    2K citations

  6. University of California San Diego

    San Diego, United States

    6 h-index

    19 publications

    1.3K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    12 publications

    844 citations

  8. University of Cambridge

    Cambridge, United Kingdom

    5 h-index

    28 publications

    2.3K citations

1–8 of 435

Venues

  1. PLoS ONE

    11 publications · 369 citations

    11

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 9 publications · 530 citations

    9

    h-index

  3. Cell Reports

    9 publications · 1.5K citations

    8

    h-index

  4. Nature Communications

    7 publications · 454 citations

    7

    h-index

  5. eLife

    7 publications · 724 citations

    7

    h-index

1–5