Concepedia

Primary Drying Scale-up

Primary Drying Scale-Up is a methodological framework within lyophilization engineering that systematically translates process parameters and thermal characteristics from laboratory-scale to production-scale systems during the primary drying phase, ensuring maintenance of product quality and process efficiency through geometric and dynamic similarity principles.

9

Publications

507

Citations

64

Authors

31

Institutions

Publications per year

2017–2026

3

Parents

Publications

9

Advanced approach to build the design space for the primary drying of a pharmaceutical freeze‐drying process

Davide Fissore, Roberto Pisano, Antonello Barresi · Journal of Pharmaceutical Sciences · 2011 · 111 citations

, , +15

On the Use of Mathematical Models to Build the Design Space for the Primary Drying Phase of a Pharmaceutical Lyophilization Process

Anna Giordano, Antonello Barresi, Davide Fissore · Journal of Pharmaceutical Sciences · 2010 · 107 citations · Full text

, , +16

A procedure to optimize scale-up for the primary drying phase of lyophilization

D.M. Kremer, Michael J. Pikal, William J. Petre et al. · Journal of Pharmaceutical Sciences · 2008 · 63 citations

, , +9

Uncertainty analysis as essential step in the establishment of the dynamic Design Space of primary drying during freeze-drying

Séverine Mortier, Pieter-Jan Van Bockstal, Jos Corver et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2016 · 53 citations

, , +13

Predictive models of lyophilization process for development, scale-up/tech transfer and manufacturing

Tong Zhu, Ehab M. Moussa, Madeleine Witting et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2018 · 53 citations

, , +16

1–5 of 9

Authors

64

  1. ST
    Serguei Tchessalov

    Pfizer (United States), United States

    2 publications · 64 citations

    2

    h-index

  2. ES
    Evgenyi Shalaev

    Pfizer (United States), United States

    2 publications · 99 citations

    2

    h-index

  3. AA
    Alina Alexeenko

    Purdue University West Lafayette, United States

    2 publications · 89 citations

    2

    h-index

  4. DF
    Davide Fissore

    Politecnico di Torino, Italy

    2 publications · 218 citations

    2

    h-index

  5. AB
    Antonello Barresi

    Politecnico di Torino, Italy

    2 publications · 218 citations

    2

    h-index

1–5 of 64

Institutions

31

  1. Pfizer (United States)

    New York, United States

    4 h-index

    11 publications

    516 citations

  2. AbbVie (United States)

    North Chicago, United States

    3 h-index

    12 publications

    560 citations

  3. Politecnico di Torino

    Turin, Italy

    2 h-index

    6 publications

    654 citations

  4. Purdue University West Lafayette

    West Lafayette, United States

    2 h-index

    4 publications

    178 citations

  5. Biogen (United States)

    Cambridge, United States

    1 h-index

    1 publications

    28 citations

  6. Bayer (Germany)

    Leverkusen, Germany

    1 h-index

    1 publications

    36 citations

  7. Takeda (Austria)

    Vienna, Austria

    1 h-index

    1 publications

    36 citations

  8. Merck & Co., Inc., Rahway, NJ, USA (United States)

    Rahway, United States

    1 h-index

    1 publications

    36 citations

1–8 of 31

Venues

  1. Journal of Pharmaceutical Sciences

    5 publications · 350 citations

    5

    h-index

  2. European Journal of Pharmaceutics and Biopharmaceutics

    EJPB · 2 publications · 106 citations

    2

    h-index

  3. AAPS PharmSciTech

    1 publications · 36 citations

    1

    h-index

  4. Drying Technology

    1 publications · 15 citations

    1

    h-index

1–4