Concepedia

Peptide Digestion

Peptide Digestion is a biochemical process in bottom-up proteomics whereby proteins are cleaved into smaller peptides by specific enzymes or chemical agents, enabling downstream mass spectrometric analysis for protein identification and characterization.

1.2K

Publications

71.2K

Citations

4.3K

Authors

1.2K

Institutions

Publications per year

2017–2026

194

Parents

Publications

1.2K

In-gel digestion for mass spectrometric characterization of proteins and proteomes

Andrej Shevchenko, Henrik Tomas, J. Havli et al. · Nature Protocols · 2006 · 5.1K citations

, , +14

A gas-liquid solid phase peptide and protein sequenator.

Rodney M. Hewick, Michael W. Hunkapiller, Leroy Hood et al. · Journal of Biological Chemistry · 1981 · 2.2K citations · Full text

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Internal amino acid sequence analysis of proteins separated by one- or two-dimensional gel electrophoresis after in situ protease digestion on nitrocellulose.

Ruedi H. Aebersold, John Leavitt, Rafael Saavedra et al. · Proceedings of the National Academy of Sciences · 1987 · 818 citations · Full text

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Improvement of an "In-Gel" Digestion Procedure for the Micropreparation of Internal Protein Fragments for Amino Acid Sequencing

Ulf Hellman, Christer Wernstedt, Jorge Gonez et al. · Analytical Biochemistry · 1995 · 760 citations

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Peptide Separation by Two-dimensional Chromatography and Electrophoresis

Arnold M. Katz, William J. Dreyer, Christian B. Anfinsen · Journal of Biological Chemistry · 1959 · 731 citations · Full text

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1–5 of 1.2K

Authors

4.3K

  1. EL
    Emil L. Smith

    University of Utah, United States

    15 publications · 689 citations

    13

    h-index

  2. PF
    Pasquale Ferranti

    University of Naples Federico II, Italy

    9 publications · 505 citations

    9

    h-index

  3. GM
    Gianfranco Mamone

    Institute of Food Science, Italy

    8 publications · 479 citations

    8

    h-index

  4. RM
    Richard M. Caprioli

    Vanderbilt University, United States

    8 publications · 565 citations

    8

    h-index

  5. LL
    Liang Li

    University of Alberta, Canada

    8 publications · 501 citations

    8

    h-index

1–5 of 4.3K

Institutions

1.2K

  1. Centre National de la Recherche Scientifique

    Paris, France

    14 h-index

    42 publications

    2.1K citations

  2. University of Alberta

    Edmonton, Canada

    13 h-index

    41 publications

    2.5K citations

  3. Fudan University

    Shanghai, China

    12 h-index

    62 publications

    1.5K citations

  4. Max Planck Institute of Biochemistry

    Martinsried, Germany

    12 h-index

    43 publications

    12.6K citations

  5. Chinese Academy of Sciences

    Beijing, China

    12 h-index

    85 publications

    4.3K citations

  6. University of Naples Federico II

    Naples, Italy

    12 h-index

    32 publications

    1.5K citations

  7. Dalian Institute of Chemical Physics

    Dalian, China

    12 h-index

    81 publications

    4K citations

  8. Kyoto University

    Kyoto, Japan

    11 h-index

    36 publications

    1.1K citations

1–8 of 1.2K

Venues

  1. Journal of Biological Chemistry

    JBC · 110 publications · 10.8K citations

    53

    h-index

  2. Analytical Chemistry

    77 publications · 4.7K citations

    39

    h-index

  3. Journal of Proteome Research

    JPR · 52 publications · 4.1K citations

    34

    h-index

  4. European Journal of Biochemistry

    EJB · 47 publications · 2.5K citations

    29

    h-index

  5. Journal of Agricultural and Food Chemistry

    34 publications · 2.1K citations

    25

    h-index

1–5