Concepedia

Optogenetic Therapy

Optogenetic Therapy is a form of ocular gene therapy that involves the genetic introduction of light-sensitive proteins into retinal cells to restore light responsiveness in degenerated photoreceptor layers, thereby enabling visual signal transduction through targeted optical stimulation.

305

Publications

23.9K

Citations

1.7K

Authors

553

Institutions

Publications per year

2017–2026

167

Parents

Publications

305

Gene therapy restores vision in a canine model of childhood blindness

Gregory M. Acland, Jharna Ray, Qí Zhāng et al. · Nature Genetics · 2001 · 1.2K citations

, , +16

Molecular and Cellular Approaches for Diversifying and Extending Optogenetics

Viviana Gradinaru, Feng Zhang, Charu Ramakrishnan et al. · Cell · 2010 · 1K citations · Full text

, , +12

ReaChR: a red-shifted variant of channelrhodopsin enables deep transcranial optogenetic excitation

John Y. Lin, Per Magne Knutsen, Arnaud Muller et al. · Nature Neuroscience · 2013 · 863 citations · Full text

, , +11

Partial recovery of visual function in a blind patient after optogenetic therapy

José‐Alain Sahel, Élise Boulanger-Scemama, Chloé Pagot et al. · Nature Medicine · 2021 · 690 citations

, , +12

Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri

Feng Zhang, Matthias Prigge, Florent Beyrière et al. · Nature Neuroscience · 2008 · 527 citations · Full text

, , +15

1–5 of 305

Authors

1.7K

  1. SP
    Serge Picaud

    Inserm, France

    11 publications · 1.8K citations

    11

    h-index

  2. JS
    José‐Alain Sahel

    Inserm, France

    12 publications · 1.8K citations

    11

    h-index

  3. KD
    Karl Deisseroth

    Stanford University, United States

    12 publications · 2.9K citations

    11

    h-index

  4. JD
    Jens Duebel

    Institut de la Vision, France

    10 publications · 1.6K citations

    10

    h-index

  5. DD
    Deniz Dalkara

    Institut de la Vision, France

    10 publications · 1.6K citations

    10

    h-index

1–5 of 1.7K

Institutions

553

  1. Stanford University

    Stanford, United States

    17 h-index

    102 publications

    21.2K citations

  2. Inserm

    Paris, France

    13 h-index

    128 publications

    14.1K citations

  3. Institut de la Vision

    Paris, France

    13 h-index

    139 publications

    19.9K citations

  4. Sorbonne Université

    Paris, France

    13 h-index

    132 publications

    17.9K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    13 h-index

    124 publications

    12.4K citations

  6. University College London

    London, United Kingdom

    10 h-index

    28 publications

    5.2K citations

  7. Howard Hughes Medical Institute

    Chevy Chase, United States

    10 h-index

    14 publications

    3.4K citations

  8. Newcastle University

    Newcastle upon Tyne, United Kingdom

    10 h-index

    23 publications

    726 citations

1–8 of 553

Venues

  1. Scientific Reports

    10 publications · 484 citations

    10

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 9 publications · 1.5K citations

    9

    h-index

  3. Investigative Ophthalmology & Visual Science

    IOVS · 8 publications · 504 citations

    8

    h-index

  4. Nature Communications

    8 publications · 837 citations

    8

    h-index

  5. PubMed

    Repository · 7 publications · 161 citations

    7

    h-index

1–5