Partial recovery of visual function in a blind patient after optogenetic therapy

José‐Alain Sahel, Élise Boulanger-Scemama, Chloé Pagot, +15

Nature Medicine

Partial RecoveryOphthalmologyVisual ImpairmentMedicineBlindsight +10

Genetic Reactivation of Cone Photoreceptors Restores Visual Responses in Retinitis Pigmentosa

Volker Busskamp, Jens Duebel, D. Bálya, +16

Science

BiologyGanglion CellPhotoreceptor CellSignal TransductionRetina +12

Characterizing Light-Regulated Retinal MicroRNAs Reveals Rapid Turnover as a Common Property of Neuronal MicroRNAs

Jacek Król, Volker Busskamp, Ilona Markiewicz, +12

Cell

Photoreceptor CellMolecular NeuroscienceRetinaOphthalmologyNeuronal Micrornas +8

A spike sorting toolbox for up to thousands of electrodes validated with ground truth recordings in vitro and in vivo

Pierre Yger, Giulia Lb Spampinato, Elric Esposito, +9

eLife

EngineeringGround Truth RecordingsNeural RecodingBiomedical EngineeringLarge Silicon Probes +19

The Primordial, Blue-Cone Color System of the Mouse Retina

Silke Haverkamp, Heinz Wässle, Jens Duebel, +4

Journal of Neuroscience

Functional Fluorescent Ca2+ Indicator Proteins in Transgenic Mice under TET Control

Mazahir T. Hasan, Rainer W. Friedrich, Thomas Euler, +11

PLoS Biology

NeurotransmitterNeurotransmissionTransgenic MiceOptogeneticsSynaptic Signaling +21

Generation of Storable Retinal Organoids and Retinal Pigmented Epithelium from Adherent Human iPS Cells in Xeno-Free and Feeder-Free Conditions

Sacha Reichman, Amélie Slembrouck, Giuliana Gagliardi, +11

Stem Cells

Targeting Channelrhodopsin-2 to ON-bipolar Cells With Vitreally Administered AAV Restores ON and OFF Visual Responses in Blind Mice

Émilie Macé, Romain Caplette, Olivier Marre, +9

Molecular Therapy

Red‐shifted channelrhodopsin stimulation restores light responses in blind mice, macaque retina, and human retina

Abhishek Sengupta, Antoine Chaffiol, Émilie Macé, +10

EMBO Molecular Medicine

Two-Photon Imaging Reveals Somatodendritic Chloride Gradient in Retinal ON-Type Bipolar Cells Expressing the Biosensor Clomeleon

Jens Duebel, Silke Haverkamp, Wolfram Schleich, +4

Neuron

Biosensor ClomeleonGanglion CellPhotoreceptor CellEngineeringRetina +8