ReaChR: a red-shifted variant of channelrhodopsin enables deep transcranial optogenetic excitation

Millisecond-timescale, genetically targeted optical control of neural activity

Edward S. Boyden, Feng Zhang, Ernst Bamberg et al. · Nature Neuroscience · 2005 · 4.9K citations

Life Sciences, Neurobiology, Neuroscience +12

Channelrhodopsin-2, a directly light-gated cation-selective membrane channel

Georg Nagel, Tanjef Szellas, Wolfram Huhn et al. · Proceedings of the National Academy of Sciences · 2003 · 2.7K citations · Full text

Life Sciences, Biology, Biophysics +17

Neocortical excitation/inhibition balance in information processing and social dysfunction

Ofer Yizhar, Lief E. Fenno, Matthias Prigge et al. · Nature · 2011 · 2.5K citations

Life Sciences, Neurobiology, Neuroscience +16

Neural substrates of awakening probed with optogenetic control of hypocretin neurons

Antoine Adamantidis, Feng Zhang, Alexander M. Aravanis et al. · Nature · 2007 · 1.3K citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Long-term dendritic spine stability in the adult cortex

Jaime Grutzendler, Narayanan Kasthuri, Wen‐Biao Gan · Nature · 2002 · 1.2K citations

Life Sciences, Neurobiology, Neuroscience +14