Concepedia

No-observed-adverse-effect Level

No-Observed-Adverse-Effect Level is a toxicological threshold representing the highest administered or environmental dose of a substance at which no statistically or biologically significant adverse effects are observed in an experimental population under defined exposure conditions.

537

Publications

22.9K

Citations

2.7K

Authors

772

Institutions

Publications per year

2017–2026

149

Variants

Noael

Parents

Publications

537

Effects of the synthetic estrogen 17α-ethinylestradiol on the life-cycle of the fathead minnow (<i>Pimephales promelas</i>)

R. Länge, Thomas H. Hutchinson, Charlotte P. Croudace et al. · Environmental Toxicology and Chemistry · 2001 · 640 citations · Full text

, , +17

Efficacy and safety of vitamin D3 intake exceeding the lowest observed adverse effect level

Reinhold Vieth, Pak-Cheung Chan, Gordon D. MacFarlane · American Journal of Clinical Nutrition · 2001 · 615 citations · Full text

, , +14

Toxicological screening

Subramani Parasuraman · Journal of Pharmacology and Pharmacotherapeutics · 2011 · 533 citations · Full text

, , +17

Correlation of structural class with no-observed-effect levels: A proposal for establishing a threshold of concern

I.C. Munro, R.A. Ford, Elke Kennepohl et al. · Food and Chemical Toxicology · 1996 · 492 citations

, , +9

Dose-Dependent Alterations in Androgen-Regulated Male Reproductive Development in Rats Exposed to Di(n-butyl) Phthalate during Late Gestation

Eve Mylchreest · Toxicological Sciences · 2000 · 452 citations · Full text

, , +17

1–5 of 537

Authors

2.7K

  1. MJ
    María José Frutos Fernández

    Universitat de Miguel Hernández d'Elx, Spain

    9 publications · 445 citations

    9

    h-index

  2. YS
    Yolanda Sanz

    Instituto de Agroquímica y Tecnología de Alimentos, Spain

    8 publications · 266 citations

    8

    h-index

  3. MH
    Marina Heinonen

    University of Helsinki, Finland

    8 publications · 264 citations

    8

    h-index

  4. PM
    Peter Moldéus

    Karolinska Institutet, Sweden

    8 publications · 404 citations

    8

    h-index

  5. AN
    Androniki Naska

    National and Kapodistrian University of Athens, Greece

    8 publications · 264 citations

    8

    h-index

1–5 of 2.7K

Institutions

772

  1. Environmental Protection Agency

    Washington, United States

    18 h-index

    76 publications

    3.6K citations

  2. Research Triangle Park Foundation

    Durham, United States

    12 h-index

    32 publications

    2.3K citations

  3. National Center for Toxicological Research

    Pine Bluff, United States

    11 h-index

    27 publications

    2.5K citations

  4. United States Food and Drug Administration

    Silver Spring, United States

    11 h-index

    22 publications

    1.4K citations

  5. Health Canada

    Ottawa, Canada

    8 h-index

    36 publications

    1.6K citations

  6. DuPont (United States)

    Wilmington, United States

    8 h-index

    26 publications

    658 citations

  7. Charles River Laboratories (United States)

    Wilmington, United States

    8 h-index

    15 publications

    676 citations

  8. Ashland (United States)

    Covington, United States

    7 h-index

    14 publications

    641 citations

1–8 of 772

Venues

  1. Toxicological Sciences

    28 publications · 2K citations

    23

    h-index

  2. International Journal of Toxicology

    IJT · 36 publications · 1.5K citations

    22

    h-index

  3. EFSA Journal

    27 publications · 1.5K citations

    20

    h-index

  4. Environmental Toxicology and Chemistry

    24 publications · 1.5K citations

    19

    h-index

  5. Toxicology Reports

    18 publications · 544 citations

    15

    h-index

1–5