Concepedia

Mitochondrial Bottlenecks

Mitochondrial Bottlenecks is a biological phenomenon in mitochondrial inheritance characterized by a drastic reduction in the number of mitochondrial DNA copies transmitted from mother to offspring, leading to increased stochastic variation in mitochondrial genome segregation across generations.

50

Publications

5.2K

Citations

325

Authors

170

Institutions

Publications per year

2017–2026

10

Variants

Mitochondrial Dna BottleneckMitochondrial Genetic Bottleneck

Parents

Publications

50

The mitochondrial DNA genetic bottleneck results from replication of a subpopulation of genomes

Timothy Wai, Daniella Teoli, Eric A. Shoubridge · Nature Genetics · 2008 · 468 citations

, , +12

Mother's curse: the effect of mtDNA on individual fitness and population viability

Neil J. Gemmell, Victoria Metcalf, Fred W. Allendorf · Trends in Ecology & Evolution · 2004 · 428 citations

, , +14

The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells

Liqin Cao, Hiroshi Shitara, Takuro Horii et al. · Nature Genetics · 2007 · 354 citations

, , +15

Abundant mitochondrial DNA variation and world-wide population structure in humpback whales.

C. Scott Baker, Anjanette Perry, JL Bannister et al. · Proceedings of the National Academy of Sciences · 1993 · 321 citations

, , +17

Maternal age effect and severe germ-line bottleneck in the inheritance of human mitochondrial DNA

Boris Rebolledo‐Jaramillo, Marcia Shu‐Wei Su, Nicholas Stoler et al. · Proceedings of the National Academy of Sciences · 2014 · 264 citations · Full text

, , +15

1–5 of 50

Authors

325

  1. IG
    Iain G. Johnston

    University of Bergen, Norway

    4 publications · 226 citations

    4

    h-index

  2. DC
    David C. Samuels

    Vanderbilt University, United States

    4 publications · 273 citations

    4

    h-index

  3. IM
    Ian M. Paul

    Penn State Milton S. Hershey Medical Center, United States

    3 publications · 417 citations

    3

    h-index

  4. KD
    Kateryna D. Makova

    Pennsylvania State University, United States

    3 publications · 417 citations

    3

    h-index

  5. JP
    Joanna Poulton

    University of Oxford, United Kingdom

    3 publications · 296 citations

    3

    h-index

1–5 of 325

Institutions

170

  1. University of Bergen

    Bergen, Norway

    4 h-index

    9 publications

    473 citations

  2. Newcastle University

    Newcastle upon Tyne, United Kingdom

    4 h-index

    11 publications

    1.9K citations

  3. University of Oxford

    Oxford, United Kingdom

    4 h-index

    12 publications

    1.2K citations

  4. University of California, Berkeley

    Berkeley, United States

    3 h-index

    6 publications

    834 citations

  5. Wellcome Centre for Mitochondrial Research

    Newcastle upon Tyne, United Kingdom

    3 h-index

    11 publications

    1.3K citations

  6. Pennsylvania State University

    State College, United States

    3 h-index

    14 publications

    1.9K citations

  7. Tokyo Metropolitan Institute of Medical Science

    Tokyo, Japan

    3 h-index

    8 publications

    1.8K citations

  8. Vanderbilt University Medical Center

    Nashville, United States

    3 h-index

    4 publications

    251 citations

1–8 of 170

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 4 publications · 929 citations

    4

    h-index

  2. PLoS ONE

    3 publications · 127 citations

    3

    h-index

  3. The American Journal of Human Genetics

    AJHG · 3 publications · 296 citations

    3

    h-index

  4. Genetics

    2 publications · 246 citations

    2

    h-index

  5. Conservation Genetics

    2 publications · 78 citations

    2

    h-index

1–5