David C. Samuels

Pathogenic Mitochondrial DNA Mutations Are Common in the General Population

Hannah R. Elliott, David C. Samuels, James A. Eden et al. · The American Journal of Human Genetics · 2008 · 599 citations · Full text

Mitochondrial DNA mutations in human colonic crypt stem cells

Robert W. Taylor, Martin Barron, Gillian M. Borthwick et al. · Journal of Clinical Investigation · 2003 · 518 citations · Full text

Essential Subunits, Genome Instability, Respiratory Chain +12

A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes

Lynsey Cree, David C. Samuels, Susana M. Chuva de Sousa Lopes et al. · Nature Genetics · 2008 · 505 citations

Developmental Biology, Rapid Segregation, Cell Division +10

Universal heteroplasmy of human mitochondrial DNA

Brendan Payne, Ian Wilson, Patrick Yu‐Wai‐Man et al. · Human Molecular Genetics · 2012 · 432 citations · Full text

Dna, Mitochondrial Biogenesis, Mitochondrial Function +12

Random Intracellular Drift Explains the Clonal Expansion of Mitochondrial DNA Mutations with Age

Joanna L. Elson, David C. Samuels, Douglass M. Turnbull et al. · The American Journal of Human Genetics · 2001 · 340 citations · Full text

Biology, Genome Instability, Mitochondrial Function +11