Concepedia

Maturation Pathways

Maturation Pathways is a theoretical framework in immunology that delineates the sequential molecular and cellular events through which B cells undergo affinity maturation in germinal centers, distinguishing it from related models by specifying the dynamic trajectories of somatic hypermutation and selection that lead to high-affinity antibody production.

123

Publications

8.6K

Citations

696

Authors

282

Institutions

Publications per year

2017–2026

22

Parents

Publications

123

Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation

Didrik Paus, Tri Giang Phan, Tyani D. Chan et al. · The Journal of Experimental Medicine · 2006 · 541 citations · Full text

, , +17

Human memory B cells originate from three distinct germinal center-dependent and -independent maturation pathways

Magdalena A. Berkowska, Gertjan J. Driessen, Vasilis Bikos et al. · Blood · 2011 · 367 citations · Full text

, , +15

Physiological and Behavioral Changes in Honey Bees (Apis mellifera) Induced by Nosema ceranae Infection

Mike Goblirsch, Marla Spivak · PLoS ONE · 2013 · 297 citations · Full text

, , +15

Differentiation of germinal center B cells into plasma cells is initiated by high-affinity antigen and completed by Tfh cells

Nike Julia Kräutler, Dan Suan, Danyal Butt et al. · The Journal of Experimental Medicine · 2017 · 290 citations · Full text

, , +17

Genomic dissection of behavioral maturation in the honey bee

Charles W. Whitfield, Yehuda Ben‐Shahar, Charles Brillet et al. · Proceedings of the National Academy of Sciences · 2006 · 265 citations · Full text

, , +15

1–5 of 123

Authors

696

  1. GE
    Gene E. Robinson

    University of Illinois Urbana-Champaign, United States

    5 publications · 495 citations

    5

    h-index

  2. TB
    Thomas B. Kepler

    Duke University, United States

    4 publications · 386 citations

    4

    h-index

  3. WC
    Weizao Chen

    National Cancer Institute, United States

    4 publications · 146 citations

    4

    h-index

  4. DS
    Dimiter S. Dimitrov

    National Cancer Institute, United States

    4 publications · 146 citations

    4

    h-index

  5. BF
    Barton F. Haynes

    Duke University, United States

    4 publications · 386 citations

    4

    h-index

1–5 of 696

Institutions

282

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    10 h-index

    19 publications

    2.1K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    7 h-index

    24 publications

    792 citations

  3. Harvard University

    Cambridge, United States

    7 h-index

    26 publications

    1.7K citations

  4. National Institutes of Health

    Bethesda, United States

    7 h-index

    31 publications

    1.2K citations

  5. National Cancer Institute

    Bethesda, United States

    6 h-index

    16 publications

    631 citations

  6. Center for Cancer Research

    Bethesda, United States

    5 h-index

    15 publications

    589 citations

  7. University of Illinois Urbana-Champaign

    Urbana, United States

    5 h-index

    14 publications

    1.7K citations

  8. Scripps Research Institute

    San Diego, United States

    5 h-index

    44 publications

    2.4K citations

1–8 of 282

Venues

  1. The Journal of Immunology

    JI · 9 publications · 667 citations

    9

    h-index

  2. The Journal of Experimental Medicine

    7 publications · 1.3K citations

    7

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 7 publications · 952 citations

    7

    h-index

  4. European Journal of Immunology

    EJI · 5 publications · 152 citations

    5

    h-index

  5. PubMed

    Repository · 5 publications · 282 citations

    5

    h-index

1–5