Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption

Michelle M. McDonald, Weng Hua Khoo, Pei Ying Ng, +44

Cell

MechanobiologyDevelopmental BiologyRankl-stimulated Bone ResorptionRankl-stimulated OsteoclastsDaughter Cells +13

Differentiation of germinal center B cells into plasma cells is initiated by high-affinity antigen and completed by Tfh cells

Nike Julia Kräutler, Dan Suan, Danyal Butt, +10

The Journal of Experimental Medicine

Developmental BiologyPlasma CellsLymphocyte DevelopmentTfh CellsImmunology +12

CCR6 Defines Memory B Cell Precursors in Mouse and Human Germinal Centers, Revealing Light-Zone Location and Predominant Low Antigen Affinity

Dan Suan, Nike Julia Kräutler, Jesper L.V. Mååg, +11

Immunity

Signal TransductionCell InteractionImmunologyMedicineCell Biology +4

Elimination of Germinal-Center-Derived Self-Reactive B Cells Is Governed by the Location and Concentration of Self-Antigen

Tyani D. Chan, Katherine C. Wood, Jana R. Hermes, +4

Immunity

Autoimmune DiseaseHumoral ResponseImmunologyAntigen ProcessingAutoimmunity +6

Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes

Imogen Moran, Akira Nguyen, Weng Hua Khoo, +17

Nature Communications

Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption

Michelle M. McDonald, Weng Hua Khoo, Pei Ying Ng, +44

Cell

Germline-activating mutations in <i>PIK3CD</i> compromise B cell development and function

Danielle T. Avery, Alisa Kane, Tina Nguyen, +30

The Journal of Experimental Medicine

FAS Inactivation Releases Unconventional Germinal Center B Cells that Escape Antigen Control and Drive IgE and Autoantibody Production

Danyal Butt, Tyani D. Chan, Katherine Bourne, +14

Immunity

Drive IgeAutoimmune DiseaseEscape Antigen ControlAutoantibody ProductionAdaptive Immune System +9

Positive selection of IgG+ over IgM+ B cells in the germinal center reaction

Christopher Sundling, Angelica W.Y. Lau, Katherine Bourne, +8

Immunity

Signal TransductionCell DivisionCell InteractionPositive SelectionImmunoglobulin E +6

An anti-TL1A antibody for the treatment of asthma and inflammatory bowel disease

Adam W. Clarke, Lynn D. Poulton, Doris Shim, +8

mAbs

AsthmaImmunologyImmune RegulationImmunologic MechanismImmunotherapy +15