Concepedia

Lymphedema Pathophysiology

Lymphedema Pathophysiology is the branch of medical pathophysiology that investigates the mechanisms by which impaired lymphatic transport leads to protein-rich interstitial fluid accumulation, chronic inflammation, fibrosis, and adipose tissue deposition, thereby producing the clinical phenotype and progression of lymphedema.

801

Publications

44.4K

Citations

3.4K

Authors

1K

Institutions

Publications per year

2017–2026

211

Variants

Pathophysiology Of Lymphedema

Parents

Children

Publications

801

Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3

Taija Mäkinen, Lotta Jussila, Tanja Veikkola et al. · Nature Medicine · 2001 · 780 citations

, , +13

T1α/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema

Vivien Schacht, María I. Ramirez, Satoshi Hirakawa et al. · The EMBO Journal · 2003 · 669 citations · Full text

, , +8

Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema

Marika J. Karkkainen, Robert E. Ferrell, Elizabeth Lawrence et al. · Nature Genetics · 2000 · 654 citations

, , +7

Mutations in FOXC2 (MFH-1), a Forkhead Family Transcription Factor, Are Responsible for the Hereditary Lymphedema-Distichiasis Syndrome

Jianming Fang, Susan L. Dagenais, Robert P. Erickson et al. · The American Journal of Human Genetics · 2000 · 613 citations · Full text

, , +10

A model for gene therapy of human hereditary lymphedema

Marika J. Karkkainen, Anne Saaristo, Lotta Jussila et al. · Proceedings of the National Academy of Sciences · 2001 · 611 citations · Full text

, , +17

1–5 of 801

Authors

3.4K

  1. BJ
    Babak J. Mehrara

    Memorial Sloan Kettering Cancer Center, United States

    25 publications · 2.3K citations

    23

    h-index

  2. SG
    Stanley G. Rockson

    Stanford University, United States

    27 publications · 2K citations

    23

    h-index

  3. KA
    Kari Alitalo

    University of Helsinki, Finland

    17 publications · 4.7K citations

    17

    h-index

  4. PM
    Peter Mortimer

    St George's, University of London, United Kingdom

    20 publications · 2K citations

    16

    h-index

  5. WL
    Waldemar L. Olszewski

    Polish Academy of Sciences, Poland

    17 publications · 722 citations

    14

    h-index

1–5 of 3.4K

Institutions

1K

  1. Stanford University

    Stanford, United States

    23 h-index

    102 publications

    10.4K citations

  2. Memorial Sloan Kettering Cancer Center

    New York, United States

    23 h-index

    184 publications

    15.4K citations

  3. University of Arizona

    Tucson, United States

    20 h-index

    71 publications

    5.8K citations

  4. University of Helsinki

    Helsinki, Finland

    17 h-index

    50 publications

    12.8K citations

  5. Harvard University

    Cambridge, United States

    16 h-index

    89 publications

    9.3K citations

  6. Boston Children's Hospital

    Boston, United States

    15 h-index

    58 publications

    2.2K citations

  7. University Hospital of Zurich

    Zurich, Switzerland

    15 h-index

    51 publications

    2K citations

  8. St George's, University of London

    London, United Kingdom

    14 h-index

    65 publications

    6K citations

1–8 of 1K

Venues

  1. PubMed

    Repository · 130 publications · 4.4K citations

    38

    h-index

  2. Lymphatic Research and Biology

    64 publications · 2.5K citations

    28

    h-index

  3. Plastic & Reconstructive Surgery

    22 publications · 1.3K citations

    20

    h-index

  4. PLoS ONE

    14 publications · 1.4K citations

    14

    h-index

  5. Journal of Clinical Investigation

    JCI · 13 publications · 1.3K citations

    13

    h-index

1–5