Concepedia

Light Chain Coexpression

Light Chain Coexpression is a recombinant antibody expression method that involves the simultaneous expression of the antibody light chain alongside the heavy chain in a host system to enable proper assembly and functional integrity of the full-length immunoglobulin.

59

Publications

2.9K

Citations

332

Authors

117

Institutions

Publications per year

2017–2026

5

Parents

Publications

59

EBF and E47 Collaborate to Induce Expression of the Endogenous Immunoglobulin Surrogate Light Chain Genes

Mikael Sigvardsson, Mary O’Riordan, Rudolf Grosschedl · Immunity · 1997 · 274 citations · Full text

, , +5

Activity of multiple light chain genes in murine myeloma cells producing a single, functional light chain

Frederick W. Alt, Vincenzo Enea, Alfred L.M. Bothwell et al. · Cell · 1980 · 229 citations · Full text

, , +6

Progressive resistance training reduces myosin heavy chain coexpression in single muscle fibers from older men

David L. Williamson, Michael P. Godard, David Porter et al. · Journal of Applied Physiology · 2000 · 130 citations

, , +17

Structure, function, and regulation of human cystine/glutamate transporter in retinal pigment epithelial cells.

Christy C. Bridges, Ramesh Kekuda, H Wang et al. · PubMed · 2001 · 127 citations

, , +13

Coexpression of factor VIII heavy and light chain adeno-associated viral vectors produces biologically active protein

Melissa Burton, Hiroyuki Nakai, Peter Colosi et al. · Proceedings of the National Academy of Sciences · 1999 · 103 citations

, , +14

1–5 of 59

Authors

332

  1. AH
    Arnold H. Horwitz

    XOMA (United States), United States

    2 publications · 60 citations

    2

    h-index

  2. SL
    Sherie L. Morrison

    University of California, Los Angeles, United States

    2 publications · 52 citations

    2

    h-index

  3. RK
    Ramesh Kekuda

    Augusta University, United States

    2 publications · 200 citations

    2

    h-index

  4. WH
    Wei Huang

    Augusta University, United States

    2 publications · 200 citations

    2

    h-index

  5. PD
    Puttur D. Prasad

    Augusta University, United States

    2 publications · 200 citations

    2

    h-index

1–5 of 332

Institutions

117

  1. Stanford University

    Stanford, United States

    3 h-index

    11 publications

    658 citations

  2. Augusta University

    Augusta, United States

    2 h-index

    9 publications

    711 citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    4 publications

    310 citations

  4. University of Alabama at Birmingham

    Birmingham, United States

    2 h-index

    4 publications

    295 citations

  5. Princeton University

    Princeton, United States

    2 h-index

    6 publications

    484 citations

  6. Inserm

    Paris, France

    2 h-index

    8 publications

    470 citations

  7. Institute of Molecular and Clinical Ophthalmology Basel

    Basel, Switzerland

    2 h-index

    2 publications

    73 citations

  8. University of Turin

    Turin, Italy

    2 h-index

    3 publications

    218 citations

1–8 of 117

Venues

  1. PubMed

    Repository · 6 publications · 242 citations

    6

    h-index

  2. European Journal of Immunology

    EJI · 4 publications · 161 citations

    4

    h-index

  3. Molecular Immunology

    3 publications · 90 citations

    3

    h-index

  4. The Journal of Experimental Medicine

    3 publications · 178 citations

    3

    h-index

  5. Journal of Biological Chemistry

    JBC · 2 publications · 89 citations

    2

    h-index

1–5