Hiroyuki Nakai

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

Catherine S. Manno, Glenn F. Pierce, Valder R. Arruda et al. · Nature Medicine · 2006 · 2.1K citations

Inflammation, Aav-factor Ix, Host Response +11

Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8

Katsuya Inagaki, Sally Fuess, Theresa A. Storm et al. · Molecular Therapy · 2006 · 585 citations · Full text

Extrachromosomal Recombinant Adeno-Associated Virus Vector Genomes Are Primarily Responsible for Stable Liver Transduction In Vivo

Hiroyuki Nakai, Stephen R. Yant, Theresa A. Storm et al. · Journal of Virology · 2001 · 474 citations · Full text

AAV serotype 2 vectors preferentially integrate into active genes in mice

Hiroyuki Nakai, Eugenio Montini, Sally Fuess et al. · Nature Genetics · 2003 · 386 citations

Active Genes, Genetics, Pathogenesis +10

Unrestricted Hepatocyte Transduction with Adeno-Associated Virus Serotype 8 Vectors in Mice

Hiroyuki Nakai, Sally Fuess, Theresa A. Storm et al. · Journal of Virology · 2004 · 317 citations · Full text

Liver Transduction, Portal Vein Injection, Hepatology +14