Concepedia

Ligand-receptor Affinity

Ligand-Receptor Affinity is a quantitative measure of the strength of interaction between a ligand and its target receptor, distinguished by its ability to characterize the binding specificity within molecular recognition processes.

2.5K

Publications

172.2K

Citations

10.8K

Authors

1.8K

Institutions

Publications per year

2017–2026

167

Variants

Receptor-ligand Affinity

Parents

Publications

2.5K

An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

Jürgen M. Lehmann, Linda B. Moore, Tracey Smith-Oliver et al. · Journal of Biological Chemistry · 1995 · 3.6K citations · Full text

, , +14

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

Avner Yayon, Michael Klagsbrun, Jeffrey D. Esko et al. · Cell · 1991 · 2.4K citations

, , +15

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

Richard A. Heyman, David J. Mangelsdorf, Jacqueline A. Dyck et al. · Cell · 1992 · 1.8K citations

, , +11

Binding and Degradation of Low Density Lipoproteins by Cultured Human Fibroblasts

Joseph L. Goldstein, Michael S. Brown · Journal of Biological Chemistry · 1974 · 1.5K citations · Full text

, , +12

High-Resolution Epitope Mapping of hGH-Receptor Interactions by Alanine-Scanning Mutagenesis

Brian C. Cunningham, James A. Wells · Science · 1989 · 1.4K citations

, , +17

1–5 of 2.5K

Authors

10.8K

  1. KA
    Kenneth A. Jacobson

    National Institutes of Health, United States

    20 publications · 1.1K citations

    18

    h-index

  2. BW
    Bernhard Wünsch

    University of Münster, Germany

    25 publications · 888 citations

    16

    h-index

  3. FB
    Francesco Berardi

    University of Bari Aldo Moro, Italy

    18 publications · 697 citations

    15

    h-index

  4. RP
    Roberto Perrone

    University of Bari Aldo Moro, Italy

    16 publications · 651 citations

    14

    h-index

  5. DS
    Dirk Schepmann

    University of Münster, Germany

    19 publications · 547 citations

    14

    h-index

1–5 of 10.8K

Institutions

1.8K

  1. National Institutes of Health

    Bethesda, United States

    51 h-index

    421 publications

    31.7K citations

  2. Harvard University

    Cambridge, United States

    32 h-index

    133 publications

    20K citations

  3. National Institute of Diabetes and Digestive and Kidney Diseases

    Bethesda, United States

    31 h-index

    257 publications

    13.7K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    28 h-index

    78 publications

    24K citations

  5. Inserm

    Paris, France

    27 h-index

    217 publications

    12K citations

  6. Stanford University

    Stanford, United States

    25 h-index

    108 publications

    19.4K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    24 h-index

    127 publications

    8.3K citations

  8. Duke Medical Center

    Durham, United States

    20 h-index

    73 publications

    4.4K citations

1–8 of 1.8K

Venues

  1. Journal of Biological Chemistry

    JBC · 247 publications · 29.2K citations

    96

    h-index

  2. Journal of Medicinal Chemistry

    218 publications · 9.8K citations

    58

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 83 publications · 10.8K citations

    55

    h-index

  4. Endocrinology

    90 publications · 6K citations

    42

    h-index

  5. Molecular Pharmacology

    66 publications · 4.3K citations

    39

    h-index

1–5