David J. Mangelsdorf

Identification of a Nuclear Receptor for Bile Acids

Makoto Makishima, Arthur Y. Okamoto, Joyce J. Repa et al. · Science · 1999 · 2.7K citations

Life Sciences, Genetics, Molecular Biology +17

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

Richard A. Heyman, David J. Mangelsdorf, Jacqueline A. Dyck et al. · Cell · 1992 · 1.8K citations

Medicine, Medicinal Chemistry, Pharmacology +11

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

Takeshi Inagaki, Mihwa Choi, Antonio Moschetta et al. · Cell Metabolism · 2005 · 1.8K citations · Full text

Life Sciences, Molecular Biology, Physiology +16

An oxysterol signalling pathway mediated by the nuclear receptor LXRα

Bethany A. Janowski, Patricia J. Willy, Thota Rama Devi et al. · Nature · 1996 · 1.7K citations

Life Sciences, Molecular Biology, Pharmacology +11

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ

Joyce J. Repa, Guosheng Liang, Jiafu Ou et al. · Genes & Development · 2000 · 1.7K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16