Concepedia

Ligand Processing

Ligand Processing is a biochemical mechanism in the Hedgehog signaling pathway that involves the post-translational modification and proteolytic cleavage of the Hedgehog ligand to generate its active, secreted form.

59

Publications

3.6K

Citations

332

Authors

126

Institutions

Publications per year

2017–2026

17

Parents

Publications

59

Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons

Christoph Thomas, Ignacio Moraga, Doron Levin et al. · Cell · 2011 · 356 citations

, , +16

Defining HLA-II Ligand Processing and Binding Rules with Mass Spectrometry Enhances Cancer Epitope Prediction

Jennifer G. Abelin, Dewi Harjanto, Matthew Malloy et al. · Immunity · 2019 · 264 citations · Full text

, , +14

Soluble, Chloride-Terminated CdSe Nanocrystals: Ligand Exchange Monitored by <sup>1</sup>H and <sup>31</sup>P NMR Spectroscopy

Nicholas C. Anderson, Jonathan S. Owen · Chemistry of Materials · 2012 · 172 citations

, , +17

The fucosyltransferase FucT-VII regulates E-selectin ligand synthesis in human T cells.

Randall N. Knibbs, Ronald A. Craig, Shunji Natsuka et al. · The Journal of Cell Biology · 1996 · 172 citations · Full text

, , +15

Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP

B. Bishop, A.R. Aricescu, Karl Harlos et al. · Nature Structural & Molecular Biology · 2009 · 136 citations · Full text

, , +13

1–5 of 59

Authors

332

  1. AS
    Adrian Salic

    Harvard University, United States

    3 publications · 240 citations

    3

    h-index

  2. KG
    Kay Grobe

    University of Münster, Germany

    2 publications · 58 citations

    2

    h-index

  3. SP
    Scott P. Goulding

    University of California, Santa Barbara, United States

    2 publications · 278 citations

    2

    h-index

  4. TA
    Terri A. Addona

    Broad Institute, United States

    2 publications · 278 citations

    2

    h-index

  5. BM
    Bradley M. Wierbowski

    Harvard University, United States

    2 publications · 111 citations

    2

    h-index

1–5 of 332

Institutions

126

  1. Harvard University

    Cambridge, United States

    6 h-index

    20 publications

    1.8K citations

  2. University of Münster

    Münster, Germany

    3 h-index

    20 publications

    584 citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    6 publications

    444 citations

  4. Memorial Sloan Kettering Cancer Center

    New York, United States

    2 h-index

    4 publications

    164 citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    2 h-index

    10 publications

    2K citations

  6. Hospital for Special Surgery

    New York, United States

    2 h-index

    5 publications

    133 citations

  7. Weizmann Institute of Science

    Rehovot, Israel

    2 h-index

    7 publications

    1.1K citations

  8. Massachusetts Institute of Technology

    Cambridge, United States

    2 h-index

    2 publications

    126 citations

1–8 of 126

Venues

  1. Journal of Biological Chemistry

    JBC · 6 publications · 433 citations

    6

    h-index

  2. Journal of Cell Science

    3 publications · 123 citations

    3

    h-index

  3. Organometallics

    3 publications · 79 citations

    3

    h-index

  4. Immunity

    2 publications · 278 citations

    2

    h-index

  5. Development

    2 publications · 124 citations

    2

    h-index

1–5