Bradley M. Wierbowski

Structural Basis of Smoothened Activation in Hedgehog Signaling

Pengxiang Huang, Sanduo Zheng, Bradley M. Wierbowski et al. · Cell · 2018 · 187 citations · Full text

Signal Transduction, Developmental Biology, Signaling Pathway +7

Hedgehog Pathway Activation Requires Coreceptor-Catalyzed, Lipid-Dependent Relay of the Sonic Hedgehog Ligand

Bradley M. Wierbowski, Kostadin Petrov, Laura Aravena et al. · Developmental Cell · 2020 · 82 citations · Full text

Molecular Physiology, Signal Transduction, Biochemistry +8

Morphogenesis of neurons and glia within an epithelium

Isabel I. C. Low, Claire Williams, Megan K. Chong et al. · Development · 2019 · 57 citations · Full text

Distinct Cation Gradients Power Cholesterol Transport at Different Key Points in the Hedgehog Signaling Pathway

Kostadin Petrov, Bradley M. Wierbowski, Jingjing Liu et al. · Developmental Cell · 2020 · 50 citations · Full text

Signal Transduction, Oxysterol, Biochemistry +11

Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release

Wanqiu Li, Linlin Wang, Bradley M. Wierbowski et al. · Nature Communications · 2021 · 26 citations · Full text