Concepedia

Library Deconvolution

Library Deconvolution is a systematic analytical process in combinatorial chemistry whereby the active constituent of a compound library is identified through iterative synthesis and screening to distinguish its biological or chemical activity from that of its library siblings.

29

Publications

2.3K

Citations

149

Authors

66

Institutions

Publications per year

2017–2026

4

Parents

Children

Publications

29

A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis

Thomas A. Down, Vardhman K. Rakyan, Daniel J. Turner et al. · Nature Biotechnology · 2008 · 648 citations · Full text

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Palladium-based mass tag cell barcoding with a doublet-filtering scheme and single-cell deconvolution algorithm

Eli R. Zunder, Rachel Finck, Gregory K. Behbehani et al. · Nature Protocols · 2015 · 624 citations · Full text

, , +11

Strategies for the Use of Mixture-Based Synthetic Combinatorial Libraries: Scaffold Ranking, Direct Testing In Vivo, and Enhanced Deconvolution by Computational Methods

Richard A. Houghten, Clemencia Pinilla, Marc A. Giulianotti et al. · Journal of Combinatorial Chemistry · 2007 · 118 citations

, , +11

Recursive deconvolution of combinatorial chemical libraries.

Eric Erb, Kim D. Janda, Sydney Brenner · Proceedings of the National Academy of Sciences · 1994 · 93 citations · Full text

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Randomness in DNA Encoded Library Selection Data Can Be Modeled for More Reliable Enrichment Calculation

Letian Kuai, Thomas O’Keeffe, Christopher C. Arico-Muendel · SLAS DISCOVERY · 2018 · 80 citations · Full text

, , +12

1–5 of 29

Authors

149

  1. JR
    Jacqueline R. Wyatt

    Ionis Pharmaceuticals (United States), United States

    3 publications · 122 citations

    3

    h-index

  2. SM
    Susan M. Freier

    Ionis Pharmaceuticals (United States), United States

    3 publications · 122 citations

    3

    h-index

  3. DJ
    David J. Ecker

    Ionis Pharmaceuticals (United States), United States

    3 publications · 122 citations

    3

    h-index

  4. DK
    Danielle Konings

    University of Colorado Boulder, United States

    2 publications · 47 citations

    2

    h-index

  5. ÁF
    Árpád Furka

    Eötvös Loránd University, Hungary

    2 publications · 57 citations

    2

    h-index

1–5 of 149

Institutions

66

  1. Ionis Pharmaceuticals (United States)

    Carlsbad, United States

    3 h-index

    21 publications

    1K citations

  2. University College London

    London, United Kingdom

    2 h-index

    3 publications

    1.4K citations

  3. Wellcome Sanger Institute

    Cambridge, United Kingdom

    2 h-index

    9 publications

    4.7K citations

  4. University of California, Los Angeles

    Los Angeles, United States

    2 h-index

    3 publications

    147 citations

  5. University of Louisville

    Louisville, United States

    2 h-index

    3 publications

    89 citations

  6. Torrey Pines Institute For Molecular Studies

    San Diego, United States

    2 h-index

    17 publications

    1.5K citations

  7. CRUK Lung Cancer Centre of Excellence

    Manchester, United Kingdom

    2 h-index

    3 publications

    1.4K citations

  8. Scripps Research Institute

    San Diego, United States

    2 h-index

    7 publications

    571 citations

1–8 of 66

Venues

  1. Journal of Medicinal Chemistry

    4 publications · 141 citations

    4

    h-index

  2. Angewandte Chemie International Edition

    2 publications · 77 citations

    2

    h-index

  3. Nature Methods

    2 publications · 107 citations

    2

    h-index

  4. 2

    h-index

  5. PubMed

    Repository · 2 publications · 45 citations

    2

    h-index

1–5