Concepedia

Positional Scanning Deconvolution

Positional Scanning Deconvolution is a combinatorial chemistry method that systematically identifies bioactive compounds in a mixture by sequentially varying and analyzing one spatial position at a time while holding others constant, thereby resolving the contribution of each positional element to the overall activity.

8

Publications

266

Citations

25

Authors

10

Institutions

Publications per year

2017–2026

0

Parents

Publications

8

Two Comparisons of the Performance of Positional Scanning and Deletion Synthesis for the Identification of Active Constituents in Mixture Combinatorial Libraries

Dale L. Boger, Jae Kyoo Lee, Joel Goldberg et al. · The Journal of Organic Chemistry · 2000 · 73 citations

, , +17

Multistep Convergent Solution-Phase Combinatorial Synthesis and Deletion Synthesis Deconvolution

Dale L. Boger, Wenying Chai, Qing Jin · Journal of the American Chemical Society · 1998 · 54 citations

, , +15

Combinatorial Libraries by Portioning and Mixing

Árpád Furka, Wendy D. Bennett · Combinatorial Chemistry & High Throughput Screening · 1999 · 32 citations

, , +14

Combinatorial Synthesis, Lead Identification, and Antitumor Study of a Chalcone‐Based Positional‐Scanning Library

Ahsan Ullah, Farzana Latif Ansari, Ihsan‐ul‐Haq et al. · Chemistry & Biodiversity · 2007 · 27 citations

, , +17

Combinatorial libraries by portioning and mixing.

Árpád Furka, Bennett Wd · PubMed · 1999 · 25 citations

, , +15

1–5 of 8

Authors

25

  1. ÁF
    Árpád Furka

    Eötvös Loránd University, Hungary

    2 publications · 57 citations

    2

    h-index

  2. QJ
    Qing Jin

    Scripps Research Institute, United States

    2 publications · 127 citations

    2

    h-index

  3. DL
    Dale L. Boger

    Scripps Research Institute, United States

    2 publications · 127 citations

    2

    h-index

  4. AU
    Ahsan Ullah

    Quaid-i-Azam University, Pakistan

    1 publications · 27 citations

    1

    h-index

  5. BM
    Bushra Mirza

    Quaid-i-Azam University, Pakistan

    1 publications · 27 citations

    1

    h-index

1–5 of 25

Institutions

10

  1. Scripps Research Institute

    San Diego, United States

    2 h-index

    7 publications

    454 citations

  2. University of Louisville

    Louisville, United States

    2 h-index

    3 publications

    89 citations

  3. Arizona Oncology

    Tucson, United States

    1 h-index

    1 publications

    17 citations

  4. University of Arizona

    Tucson, United States

    1 h-index

    2 publications

    34 citations

  5. Torrey Pines Institute For Molecular Studies

    San Diego, United States

    1 h-index

    5 publications

    85 citations

  6. Quaid-i-Azam University

    Islamabad, Pakistan

    1 h-index

    5 publications

    135 citations

  7. University of New Mexico

    Albuquerque, United States

    1 h-index

    2 publications

    34 citations

  8. Peptides International (United States)

    Louisville, United States

    1 h-index

    1 publications

    25 citations

1–8 of 10

Venues

  1. The Journal of Organic Chemistry

    JOC · 1 publications · 73 citations

    1

    h-index

  2. 1

    h-index

  3. Chemistry & Biodiversity

    1 publications · 27 citations

    1

    h-index

  4. Journal of Medicinal Chemistry

    1 publications · 21 citations

    1

    h-index

  5. PubMed

    Repository · 1 publications · 25 citations

    1

    h-index

1–5