Concepedia

Kinase Target Profiling

Kinase Target Profiling is a methodological approach in target deconvolution that specifically identifies and characterizes the binding interactions between small-molecule compounds and kinase enzymes to elucidate their selective targets within cellular signaling networks.

50

Publications

2.8K

Citations

402

Authors

113

Institutions

Publications per year

2017–2026

11

Parents

Publications

50

Cell-Based Proteome Profiling of Potential Dasatinib Targets by Use of Affinity-Based Probes

Haibin Shi, Chong‐Jing Zhang, Grace Y. J. Chen et al. · Journal of the American Chemical Society · 2012 · 233 citations

, , +17

Activity‐based kinase profiling of approved tyrosine kinase inhibitors

Daisuke Kitagawa, Koichi Yokota, Masaki Gouda et al. · Genes to Cells · 2012 · 197 citations

, , +13

Proteomic and Genetic Approaches Identify Syk as an AML Target

Cynthia K. Hahn, Jacob E. Berchuck, Kenneth N. Ross et al. · Cancer Cell · 2009 · 164 citations · Full text

, , +13

A Three-Hybrid Approach to Scanning the Proteome for Targets of Small Molecule Kinase Inhibitors

Frank Becker, Krishna K. Murthi, Chase C. Smith et al. · Chemistry & Biology · 2004 · 136 citations · Full text

, , +9

High-Throughput Kinase Profiling: A More Efficient Approach toward the Discovery of New Kinase Inhibitors

Chandrasekhar V. Miduturu, Xianming Deng, Nicholas Kwiatkowski et al. · Chemistry & Biology · 2011 · 122 citations · Full text

, , +14

1–5 of 50

Authors

402

  1. UR
    Uwe Rix

    Moffitt Cancer Center, United States

    4 publications · 215 citations

    4

    h-index

  2. DJ
    Dustin J. Maly

    University of Washington, United States

    4 publications · 145 citations

    4

    h-index

  3. NS
    Nathanael S. Gray

    Dana-Farber Cancer Institute, United States

    3 publications · 156 citations

    3

    h-index

  4. DE
    David E. Root

    Broad Institute, United States

    2 publications · 182 citations

    2

    h-index

  5. BG
    B. Gayani K. Perera

    University of Washington, United States

    2 publications · 72 citations

    2

    h-index

1–5 of 402

Institutions

113

  1. University of Washington

    Seattle, United States

    4 h-index

    24 publications

    933 citations

  2. Harvard University

    Cambridge, United States

    4 h-index

    27 publications

    3.8K citations

  3. Dana-Farber Cancer Institute

    Boston, United States

    4 h-index

    20 publications

    2.7K citations

  4. Moffitt Cancer Center

    Tampa, United States

    3 h-index

    17 publications

    719 citations

  5. University of California, Berkeley

    Berkeley, United States

    2 h-index

    8 publications

    452 citations

  6. National University of Singapore

    Singapore, Singapore

    2 h-index

    8 publications

    996 citations

  7. AstraZeneca (United Kingdom)

    Cambridge, United Kingdom

    2 h-index

    7 publications

    154 citations

  8. GlaxoSmithKline (United States)

    Philadelphia, United States

    2 h-index

    14 publications

    567 citations

1–8 of 113

Venues

  1. ACS Chemical Biology

    4 publications · 202 citations

    4

    h-index

  2. Chemistry & Biology

    3 publications · 277 citations

    3

    h-index

  3. Journal of the American Chemical Society

    JACS · 3 publications · 368 citations

    3

    h-index

  4. Molecular Cancer Therapeutics

    MCT · 2 publications · 45 citations

    2

    h-index

  5. Journal of Proteome Research

    JPR · 2 publications · 80 citations

    2

    h-index

1–5