Chase C. Smith

First total synthesis of taxol. 1. Functionalization of the B ring

Robert A. Holton, Carmen Somoza, Hyeong Baik Kim et al. · Journal of the American Chemical Society · 1994 · 627 citations

Medicinal Chemistry, Chemical Analysis, Biochemistry +14

First total synthesis of taxol. 2. Completion of the C and D rings

Robert A. Holton, Hyeong Baik Kim, Carmen Somoza et al. · Journal of the American Chemical Society · 1994 · 521 citations

Engineering, Heterocyclic, Chemical Analysis +13

A Three-Hybrid Approach to Scanning the Proteome for Targets of Small Molecule Kinase Inhibitors

Frank Becker, Krishna K. Murthi, Chase C. Smith et al. · Chemistry & Biology · 2004 · 136 citations · Full text

Molecular Docking, Three-hybrid Approach, Drug Target +9

Structure-Based Discovery of Novel Amide-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors

Xiaozhang Zheng, Paul Bauer, Timm Baumeister et al. · Journal of Medicinal Chemistry · 2013 · 80 citations · Full text

Structure-Based Identification of Ureas as Novel Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors

Xiaozhang Zheng, Paul Bauer, Timm Baumeister et al. · Journal of Medicinal Chemistry · 2013 · 68 citations · Full text

Drug Target, Biomolecular Structure Prediction, Pharmacotherapy +23