Xianming Deng

Systematic identification of genomic markers of drug sensitivity in cancer cells

Mathew J. Garnett, Elena J. Edelman, Sonja J. Heidorn et al. · Nature · 2012 · 2.5K citations · Full text

Systematic Identification, Genomic Markers, Engineering +12

A Landscape of Pharmacogenomic Interactions in Cancer

Francesco Iorio, Theo Knijnenburg, Daniël J. Vis et al. · Cell · 2016 · 2.2K citations · Full text

Tumor Biology, Oncology, Tumor Heterogeneity +13

Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity

Hongbin He, Hua Jiang, Yun Chen et al. · Nature Communications · 2018 · 746 citations · Full text

Inflammation, Covalent Nlrp3 Inhibitor, Nlrp3 Inflammasome Assembly +14

Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders

Hua Jiang, Hongbin He, Yun Chen et al. · The Journal of Experimental Medicine · 2017 · 694 citations · Full text

Direct Nlrp3 Inhibitor, Immunology, Inflammation +21

Targeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitors

Jianming Zhang, Francisco Adrián, Wolfgang Jahnke et al. · Nature · 2010 · 590 citations

Molecular Pharmacology, Drug Target, Medicine +5