Concepedia

Interferon Gamma Response

Interferon Gamma Response is a cytokine-mediated immune signaling pathway within cell-mediated immunity that is characterized by the activation of immune cells, particularly macrophages and T cells, through the binding of interferon gamma to its receptor, thereby inducing the expression of genes involved in pathogen clearance and antigen presentation.

8.9K

Publications

615.1K

Citations

39.5K

Authors

4.8K

Institutions

Publications per year

2017–2026

811

Parents

Publications

8.9K

Disseminated tuberculosis in interferon gamma gene-disrupted mice.

Andrea M. Cooper, Dyana K. Dalton, Timothy A. Stewart et al. · The Journal of Experimental Medicine · 1993 · 2K citations · Full text

, , +17

Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity.

Carl Nathan, Henry W. Murray, Michael E. Wiebe et al. · The Journal of Experimental Medicine · 1983 · 2K citations · Full text

, , +16

Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.

René de Waal Malefyt, John B.A.G. Haanen, Hergen Spits et al. · The Journal of Experimental Medicine · 1991 · 1.9K citations · Full text

, , +15

Interferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production

Clifford M. Snapper, William E. Paul · Science · 1987 · 1.9K citations

, , +17

Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression

Ángel García-Díaz, Daniel Sanghoon Shin, Blanca Homet Moreno et al. · Cell Reports · 2017 · 1.9K citations · Full text

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1–5 of 8.9K

Authors

39.5K

  1. RD
    Robert D. Schreiber

    Washington University in St. Louis, United States

    40 publications · 7.1K citations

    32

    h-index

  2. AS
    Alan Sher

    National Institute of Allergy and Infectious Diseases, United States

    30 publications · 7.3K citations

    30

    h-index

  3. JC
    Jean‐Laurent Casanova

    Inserm, France

    39 publications · 7.7K citations

    30

    h-index

  4. PA
    Peter Andersen

    Statens Serum Institut, Denmark

    34 publications · 2.7K citations

    28

    h-index

  5. SH
    Stefan H. E. Kaufmann

    Max Planck Institute for Infection Biology, Germany

    32 publications · 3.7K citations

    27

    h-index

1–5 of 39.5K

Institutions

4.8K

  1. National Institutes of Health

    Bethesda, United States

    89 h-index

    930 publications

    96.9K citations

  2. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    72 h-index

    494 publications

    69.6K citations

  3. Harvard University

    Cambridge, United States

    64 h-index

    552 publications

    61.1K citations

  4. Inserm

    Paris, France

    61 h-index

    861 publications

    103.3K citations

  5. National Cancer Institute

    Bethesda, United States

    59 h-index

    373 publications

    42.9K citations

  6. Cornell University

    Ithaca, United States

    52 h-index

    306 publications

    37.9K citations

  7. Washington University in St. Louis

    St Louis, United States

    49 h-index

    349 publications

    29.8K citations

  8. Johns Hopkins University

    Baltimore, United States

    47 h-index

    304 publications

    22.1K citations

1–8 of 4.8K

Venues

  1. Infection and Immunity

    IAI · 1.3K publications · 97.5K citations

    143

    h-index

  2. The Journal of Experimental Medicine

    197 publications · 53.5K citations

    123

    h-index

  3. Journal of Virology

    JVI · 491 publications · 36.5K citations

    103

    h-index

  4. The Journal of Immunology

    JI · 253 publications · 29K citations

    96

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 150 publications · 27.1K citations

    93

    h-index

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