Concepedia

Hla Editing

HLA Editing is a molecular bioengineering technique that belongs to the class of gene-editing methodologies and specifically entails the targeted modification of human leukocyte antigen (HLA) genes to achieve immune compatibility in allogeneic cell therapies.

14

Publications

1.3K

Citations

121

Authors

49

Institutions

Publications per year

2017–2026

12

Parents

Publications

14

Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility

Huaigeng Xu, Bo Wang, Miyuki Ono et al. · Cell stem cell · 2019 · 583 citations · Full text

, , +16

Editing of the HLA‐DR‐peptide repertoire by HLA‐DM.

Harald Kropshofer, Anne B. Vogt, G Moldenhauer et al. · The EMBO Journal · 1996 · 269 citations · Full text

, , +12

Generation of hypoimmunogenic induced pluripotent stem cells by CRISPR-Cas9 system and detailed evaluation for clinical application

Yuko Kitano, Sayaka Nishimura, Tomoaki Kato et al. · Molecular Therapy — Methods & Clinical Development · 2022 · 76 citations · Full text

, , +15

Genome-edited allogeneic donor “universal” chimeric antigen receptor T cells

Waseem Qasim · Blood · 2022 · 65 citations · Full text

, , +17

Distinct Polymorphisms in HLA Class I Molecules Govern Their Susceptibility to Peptide Editing by TAPBPR

F. Tudor Ilca, Linnea Drexhage, G. Brewin et al. · Cell Reports · 2019 · 60 citations · Full text

, , +17

1–5 of 14

Authors

121

  1. AH
    Akitsu Hotta

    Kyoto University, Japan

    2 publications · 659 citations

    2

    h-index

  2. MN
    Masaki Nomura

    Kyoto University, Japan

    2 publications · 659 citations

    2

    h-index

  3. HX
    Huaigeng Xu

    Kyoto University, Japan

    2 publications · 659 citations

    2

    h-index

  4. EA
    Esteban Arrieta‐Bolaños

    Essen University Hospital, Germany

    1 publications · 17 citations

    1

    h-index

  5. RE
    Richard E. Champlin

    The University of Texas MD Anderson Cancer Center, United States

    1 publications · 48 citations

    1

    h-index

1–5 of 121

Institutions

49

  1. Kyoto University

    Kyoto, Japan

    2 h-index

    18 publications

    9.5K citations

  2. CHA University

    Seongnam-si, South Korea

    1 h-index

    3 publications

    42 citations

  3. University College London

    London, United Kingdom

    1 h-index

    1 publications

    65 citations

  4. Ziopharm Oncology (United States)

    Boston, United States

    1 h-index

    1 publications

    48 citations

  5. Samsung Medical Center

    Seoul, South Korea

    1 h-index

    2 publications

    28 citations

  6. Bipar

    Maisons-Alfort, France

    1 h-index

    1 publications

    269 citations

  7. Agence internationale de l'énergie

    Paris, France

    1 h-index

    4 publications

    68 citations

  8. Universidad Nacional de La Plata

    La Plata, Argentina

    1 h-index

    3 publications

    51 citations

1–8 of 49

Venues

  1. Scientific Reports

    4 publications · 131 citations

    4

    h-index

  2. Cellular and Molecular Immunology

    CMI · 1 publications · 27 citations

    1

    h-index

  3. 1

    h-index

  4. Stem Cell Reviews and Reports

    1 publications · 14 citations

    1

    h-index

  5. Cell Reports

    1 publications · 60 citations

    1

    h-index

1–5