Akitsu Hotta

Stage-Specific Optimization of Activin/Nodal and BMP Signaling Promotes Cardiac Differentiation of Mouse and Human Pluripotent Stem Cell Lines

Steven Kattman, Alec Witty, Mark Gagliardi et al. · Cell stem cell · 2011 · 1.2K citations · Full text

Life Sciences, Cell Biology, Developmental Biology +16

Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility

Huaigeng Xu, Bo Wang, Miyuki Ono et al. · Cell stem cell · 2019 · 583 citations · Full text

Life Sciences, Genetics, Immunology +16

Precise Correction of the Dystrophin Gene in Duchenne Muscular Dystrophy Patient Induced Pluripotent Stem Cells by TALEN and CRISPR-Cas9

Hongmei Lisa Li, Naoko Fujimoto, Noriko Sasakawa et al. · Stem Cell Reports · 2014 · 521 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Extracellular nanovesicles for packaging of CRISPR-Cas9 protein and sgRNA to induce therapeutic exon skipping

Peter Gee, Mandy Siu Yu Lung, Yuya Okuzaki et al. · Nature Communications · 2020 · 363 citations · Full text

Life Sciences, Bioengineering, Biotechnology +17

Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency

Akitsu Hotta, Aaron Cheung, Natalie Farra et al. · Nature Methods · 2009 · 306 citations

Life Sciences, Biotechnology, Cell Biology +10