Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility

Huaigeng Xu, Bo Wang, Miyuki Ono, +13

Cell stem cell

Autoimmune DiseaseCrispr-cas9 Generates IpscsGenome SurgeryGeneticsImmunology +11

Extracellular nanovesicles for packaging of CRISPR-Cas9 protein and sgRNA to induce therapeutic exon skipping

Peter Gee, Mandy Siu Yu Lung, Yuya Okuzaki, +22

Nature Communications

CRISPR-Cas3 induces broad and unidirectional genome editing in human cells

Hiroyuki Morisaka, Kazuto Yoshimi, Yuya Okuzaki, +12

Nature Communications

Host Factor SAMHD1 Restricts DNA Viruses in Non-Dividing Myeloid Cells

Joseph A. Hollenbaugh, Peter Gee, Jonathon L. Baker, +9

PLoS Pathogens

Viral ReplicationMolecular VirologyHuman RetrovirusPathogenesisImmunology +12

Epidermal Growth Factor Receptor Activation under Oxidative Stress Fails to Promote c-Cbl Mediated Down-regulation

Tommer Ravid, Colleen Sweeney, Peter Gee, +2

Journal of Biological Chemistry

c-Cbl-mediated Ubiquitinylation Is Required for Epidermal Growth Factor Receptor Exit from the Early Endosomes

Tommer Ravid, Jill M. Heidinger, Peter Gee, +2

Journal of Biological Chemistry

Tyrosine 1045C-cbl-mediated UbiquitinylationLipid PeroxidationImmunologyRedox Biology +17

Ceramide accumulation precedes caspase-3 activation during apoptosis of A549 human lung adenocarcinoma cells

Tommer Ravid, Adili Tsaba, Peter Gee, +3

American Journal of Physiology-Lung Cellular and Molecular Physiology

Lipid PeroxidationApoptosisCell DeathCancer BiologyTumor Biology +15

Identification of Amino Acids in the Human Tetherin Transmembrane Domain Responsible for HIV-1 Vpu Interaction and Susceptibility

Tomoko Kobayashi, Hirotaka Ode, Takeshi Yoshida, +7

Journal of Virology

Essential Role of the N-terminal Domain in the Regulation of RIG-I ATPase Activity

Peter Gee, Pong Kian Chua, Jirair Gevorkyan, +4

Journal of Biological Chemistry

A study of the molecular mechanism of binding kinetics and long residence times of human <scp>CCR</scp>5 receptor small molecule allosteric ligands

David C. Swinney, Paul A. Beavis, Kai‐Ting Chuang, +11

British Journal of Pharmacology