The ribonuclease activity of SAMHD1 is required for HIV-1 restriction

Jeongmin Ryoo, Jongsu Choi, Changhoon Oh, +13

Nature Medicine

Viral ReplicationHiv-1 RestrictionHuman RetrovirusPathogenesisImmunology +6

Quantifying the Early Immune Response and Adaptive Immune Response Kinetics in Mice Infected with Influenza A Virus

Hongyu Miao, Joseph A. Hollenbaugh, Martin S. Zand, +5

Journal of Virology

Simulation and Prediction of the Adaptive Immune Response to Influenza A Virus Infection

Ha Youn Lee, David J. Topham, Sung Yong Park, +10

Journal of Virology

Tight Interplay among SAMHD1 Protein Level, Cellular dNTP Levels, and HIV-1 Proviral DNA Synthesis Kinetics in Human Primary Monocyte-derived Macrophages

Baek Kim, Laura A. Nguyen, Waaqo Daddacha, +1

Journal of Biological Chemistry

InflammationViral ReplicationHuman RetrovirusTight InterplayImmunology +9

SAMHD1 restricts HIV-1 infection in dendritic cells (DCs) by dNTP depletion, but its expression in DCs and primary CD4+T-lymphocytes cannot be upregulated by interferons

Corine St. Gelais, Suresh de Silva, Sarah M. Amie, +5

Retrovirology

Host Factor SAMHD1 Restricts DNA Viruses in Non-Dividing Myeloid Cells

Joseph A. Hollenbaugh, Peter Gee, Jonathon L. Baker, +9

PLoS Pathogens

Viral ReplicationMolecular VirologyHuman RetrovirusPathogenesisImmunology +12

Metabolite profiles of human immunodeficiency virus infected CD4+ T cells and macrophages using LC–MS/MS analysis

Joseph A. Hollenbaugh, Joshua Munger, Baek Kim

Virology

Lc–ms/ms AnalysisHuman Immunodeficiency VirusHuman RetrovirusImmunodeficienciesImmunology +11

Priming with Cold-Adapted Influenza A Does Not Prevent Infection but Elicits Long-Lived Protection against Supralethal Challenge with Heterosubtypic Virus

Timothy J. Powell, Tara M. Strutt, Joyce B. Reome, +5

The Journal of Immunology

SAMHD1 controls cell cycle status, apoptosis and HIV-1 infection in monocytic THP-1 cells

Serena Bonifati, Michele B. Daly, Corine St. Gelais, +8

Virology

Monocytic Thp-1 CellsCell DivisionCell Cycle StatusHuman RetrovirusImmunology +10

Recombinant human activated protein C inhibits integrin-mediated neutrophil migration

Gwendolyn F. Elphick, Pranita P. Sarangi, Young‐Min Hyun, +9

Blood