Gene Essentiality Mapping is a functional genomics approach that identifies the set of genes indispensable for cell survival or proliferation under specific conditions by systematically perturbing gene function and assessing phenotypic consequences.
80
Publications
7.8K
Citations
573
Authors
208
Institutions
Publications per year
2017–2026
34
Parents
Publications
80
Identification and characterization of essential genes in the human genome
Kıvanç Birsoy, Nicholas W. Hughes, Kevin M. Krupczak et al. · Science · 2015 · 1.8K citations
Genome-Wide RNAi Analysis of Growth and Viability in <i>Drosophila</i> Cells
Michael Boutros, Amy A. Kiger, Susan Armknecht et al. · Science · 2004 · 708 citations
Quality control, modeling, and visualization of CRISPR screens with MAGeCK-VISPR
Wei Li, Johannes Köster, Han Xu et al. · Genome biology · 2015 · 585 citations · Full text
The essential genome of a bacterium
Beat Christen, Eduardo Abeliuk, J.M. Collier et al. · Molecular Systems Biology · 2011 · 351 citations · Full text
Life Sciences, Biology, Genetics +7
Genome-wide CRISPR-dCas9 screens in E. coli identify essential genes and phage host factors
François Rousset, Lun Cui, Elise Siouve et al. · PLoS Genetics · 2018 · 241 citations · Full text
1–5 of 80
Authors
573
- BØ
4
h-index
- DL
4
h-index
- LS
3
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- ML
3
h-index
- SM
2
h-index
1–5 of 573
Institutions
208
Simon Fraser University
Burnaby, Canada
6 h-index
15 publications
479 citations
University of California San Diego
San Diego, United States
6 h-index
19 publications
2.9K citations
Wellcome Sanger Institute
Cambridge, United Kingdom
5 h-index
10 publications
527 citations
Centre National de la Recherche Scientifique
Paris, France
4 h-index
26 publications
3.9K citations
University of Cambridge
Cambridge, United Kingdom
4 h-index
7 publications
560 citations
Harvard University
Cambridge, United States
4 h-index
13 publications
8.8K citations
Howard Hughes Medical Institute
Chevy Chase, United States
4 h-index
14 publications
8.5K citations
University of Wisconsin–Madison
Madison, United States
3 h-index
14 publications
871 citations
1–8 of 208
Venues
- PLoS ONE
6 publications · 285 citations
6
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- Genetics
6 publications · 269 citations
6
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- PLoS Computational Biology
4 publications · 126 citations
4
h-index
- BMC Genomics
4 publications · 121 citations
4
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- BMC Systems Biology
3 publications · 347 citations
3
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1–5