Concepedia

Formulation Effect Modeling

Formulation Effect Modeling is a computational or mathematical framework within bioavailability modeling that specifically characterizes the influence of a drug's physicochemical and dosage form properties on its absorption and in vivo performance, distinguishing it from other pharmacokinetic models by isolating formulation-derived variability in drug exposure.

14

Publications

401

Citations

63

Authors

29

Institutions

Publications per year

2017–2026

5

Parents

Publications

14

Application of Dissolution/Permeation System for Evaluation of Formulation Effect on Oral Absorption of Poorly Water-Soluble Drugs in Drug Development

Makoto Kataoka, Kiyohiko Sugano, Claudia da Costa Mathews et al. · Pharmaceutical Research · 2011 · 84 citations

, , +17

Virtual bioequivalence for achlorhydric subjects: The use of PBPK modelling to assess the formulation-dependent effect of achlorhydria

Kosuke Doki, Adam S. Darwich, Nikunjkumar Patel et al. · European Journal of Pharmaceutical Sciences · 2017 · 57 citations · Full text

, , +17

Quantitative prediction of formulation-specific food effects and their population variability from in vitro data with the physiologically-based ADAM model: A case study using the BCS/BDDCS Class II drug nifedipine

Nikunjkumar Patel, Sebastian Polak, Masoud Jamei et al. · European Journal of Pharmaceutical Sciences · 2013 · 45 citations · Full text

, , +17

Properties of the estimated variance component for subject-by-formulation interaction in studies of individual bioequivalence

László Endrényi, Nathan Taback, László Tóthfalusi · Statistics in Medicine · 2000 · 28 citations

, , +17

Integrating Drug- and Formulation-Related Properties With Gastrointestinal Tract Variability Using a Product-Specific Particle Size Approach: Case Example Ibuprofen

Rodrigo Cristofoletti, Bart Hens, Nikunjkumar Patel et al. · Journal of Pharmaceutical Sciences · 2019 · 28 citations · Full text

, , +16

1–5 of 14

Authors

63

  1. NP
    Nikunjkumar Patel

    Simcyp (United Kingdom), United Kingdom

    3 publications · 130 citations

    3

    h-index

  2. AR
    Amin Rostami‐Hodjegan

    University of Manchester, United Kingdom

    2 publications · 102 citations

    2

    h-index

  3. SS
    Stephan Schmidt

    University of Florida, United States

    2 publications · 47 citations

    2

    h-index

  4. MN
    Mirjam N. Trame

    University of Florida, United States

    1 publications · 19 citations

    1

    h-index

  5. MG
    Mario González‐Sales

    PharmaMar (Spain), Spain

    1 publications · 19 citations

    1

    h-index

1–5 of 63

Institutions

29

  1. Simcyp (United Kingdom)

    Sheffield, United Kingdom

    3 h-index

    8 publications

    367 citations

  2. University of Florida

    Gainesville, United States

    2 h-index

    8 publications

    179 citations

  3. University of Manchester

    Manchester, United Kingdom

    2 h-index

    4 publications

    216 citations

  4. Springhouse

    Boston, United States

    1 h-index

    2 publications

    36 citations

  5. Kansas State University

    Manhattan, United States

    1 h-index

    1 publications

    20 citations

  6. Pfizer (United Kingdom)

    Tadworth, United Kingdom

    1 h-index

    4 publications

    336 citations

  7. University of Helsinki

    Helsinki, Finland

    1 h-index

    2 publications

    46 citations

  8. University of Toronto

    Toronto, Canada

    1 h-index

    2 publications

    56 citations

1–8 of 29

Venues

  1. The Journal of Clinical Pharmacology

    2 publications · 37 citations

    2

    h-index

  2. Journal of Pharmaceutical Sciences

    2 publications · 51 citations

    2

    h-index

  3. European Journal of Pharmaceutical Sciences

    2 publications · 102 citations

    2

    h-index

  4. The AAPS Journal

    AAPSJ · 1 publications · 12 citations

    1

    h-index

  5. The Science of The Total Environment

    1 publications · 20 citations

    1

    h-index

1–5