Concepedia

Error-prone Mutagenesis Libraries

Error-Prone Mutagenesis Libraries is a molecular biology technique-based method that introduces random mutations into antibody genes through controlled error-prone PCR or other mutagenic processes to generate diverse variant libraries for directed evolution studies.

9

Publications

597

Citations

47

Authors

22

Institutions

Publications per year

2017–2026

0

Parents

Publications

9

Why High-error-rate Random Mutagenesis Libraries are Enriched in Functional and Improved Proteins

Journal of Molecular Biology · 2005 · 143 citations · Full text

, , +13

A reliable method for random mutagenesis: the generation of mutant libraries using spiked oligodeoxyribonucleotide primers

Jeffrey D. Hermes, Shirish Parekh, Stephen C. Blacklow et al. · Gene · 1989 · 134 citations

, , +17

Enzymatic Neutralization of the Chemical Warfare Agent VX: Evolution of Phosphotriesterase for Phosphorothiolate Hydrolysis

Andrew N. Bigley, Chengfu Xu, Terry J. Henderson et al. · Journal of the American Chemical Society · 2013 · 125 citations · Full text

, , +17

Random Mutagenesis by PCR

David Sloan Wilson, Anthony D. Keefe · Current Protocols in Molecular Biology · 2000 · 108 citations

, , +15

A novel random mutagenesis approach using human mutagenic DNA polymerases to generate enzyme variant libraries

Stéphane Emond, Philippe Mondon, Sandra Pizzut‐Serin et al. · Protein Engineering Design and Selection · 2008 · 28 citations · Full text

, , +17

1–5 of 9

Authors

47

  1. SP
    Shirish Parekh

    Harvard University, United States

    1 publications · 134 citations

    1

    h-index

  2. FM
    Frank M. Raushel

    Texas A&M University, United States

    1 publications · 125 citations

    1

    h-index

  3. JR
    Jeremy R. Knowles

    Harvard University, United States

    1 publications · 134 citations

    1

    h-index

  4. PJ
    Paul J. Groot‐Kormelink

    University College London, United Kingdom

    1 publications · 13 citations

    1

    h-index

  5. TK
    Toby Kent

    Novartis (United Kingdom), United Kingdom

    1 publications · 13 citations

    1

    h-index

1–5 of 47

Institutions

22

  1. California Institute of Technology

    Pasadena, United States

    2 h-index

    3 publications

    298 citations

  2. Université Toulouse III - Paul Sabatier

    Toulouse, France

    1 h-index

    4 publications

    112 citations

  3. Harvard University

    Cambridge, United States

    1 h-index

    3 publications

    402 citations

  4. Pathways Behavioral Services

    Waterloo, United States

    1 h-index

    3 publications

    39 citations

  5. The University of Texas at Austin

    Austin, United States

    1 h-index

    2 publications

    286 citations

  6. DEVCOM Army Research Laboratory

    Adelphi, United States

    1 h-index

    2 publications

    250 citations

  7. Novartis (United States)

    New York, United States

    1 h-index

    3 publications

    39 citations

  8. Fate Therapeutics (United States)

    San Diego, United States

    1 h-index

    3 publications

    69 citations

1–8 of 22

Venues

  1. Gene

    2 publications · 157 citations

    2

    h-index

  2. Protein Engineering Design and Selection

    PEDS · 1 publications · 28 citations

    1

    h-index

  3. Journal of Molecular Biology

    JMB · 1 publications · 143 citations

    1

    h-index

  4. DNA Research

    1 publications · 11 citations

    1

    h-index

  5. PLoS ONE

    1 publications · 13 citations

    1

    h-index

1–5