Concepedia

Enzyme Recombination

Enzyme Recombination is a molecular engineering technique in directed evolution that involves the systematic reshuffling of genetic material from homologous or heterologous enzyme variants to generate chimeric enzymes with novel or enhanced catalytic properties.

14

Publications

806

Citations

70

Authors

24

Institutions

Publications per year

2017–2026

3

Parents

Publications

14

Strategies for the in vitro evolution of protein function: enzyme evolution by random recombination of improved sequences 1 1Edited by J. Wells

Jeffrey C. Moore, Hua-Ming Jin, Olga Kuchner et al. · Journal of Molecular Biology · 1997 · 161 citations

, , +13

Using a Fragment‐Based Approach To Target Protein–Protein Interactions

Duncan E. Scott, M.T. Ehebauer, Tara L. Pukala et al. · ChemBioChem · 2013 · 126 citations · Full text

, , +15

Novel enzyme activities and functional plasticity revealed by recombining highly homologous enzymes

SunAi Raillard, Anke Krebber, Yonghong Chen et al. · Chemistry & Biology · 2001 · 113 citations · Full text

, , +16

Computer‐Assisted Recombination (CompassR) Teaches us How to Recombine Beneficial Substitutions from Directed Evolution Campaigns

Haiyang Cui, Hao Cao, Haiying Cai et al. · Chemistry - A European Journal · 2019 · 79 citations · Full text

, , +15

Delivery of antibodies to the cytosol

Andrea L. J. Marschall, Congcong Zhang, André Frenzel et al. · mAbs · 2014 · 72 citations · Full text

, , +12

1–5 of 14

Authors

70

  1. KJ
    Karl‐Erich Jaeger

    Heinrich Heine University Düsseldorf, Germany

    2 publications · 118 citations

    2

    h-index

  2. US
    Ulrich Schwaneberg

    RWTH Aachen University, Germany

    2 publications · 118 citations

    2

    h-index

  3. MD
    Mehdi D. Davari

    RWTH Aachen University, Germany

    2 publications · 118 citations

    2

    h-index

  4. HC
    Haiyang Cui

    RWTH Aachen University, Germany

    2 publications · 118 citations

    2

    h-index

  5. JD
    James D. Connor

    University of California San Diego, United States

    1 publications · 17 citations

    1

    h-index

1–5 of 70

Institutions

24

  1. California Institute of Technology

    Pasadena, United States

    2 h-index

    7 publications

    692 citations

  2. Heinrich Heine University Düsseldorf

    Düsseldorf, Germany

    2 h-index

    2 publications

    118 citations

  3. DWI – Leibniz Institute for Interactive Materials

    Aachen, Germany

    2 h-index

    2 publications

    118 citations

  4. RWTH Aachen University

    Aachen, Germany

    2 h-index

    9 publications

    591 citations

  5. Directorate-General Joint Research Centre

    Brussels, Belgium

    1 h-index

    1 publications

    72 citations

  6. Hutchison/MRC Research Centre

    Cambridge, United Kingdom

    1 h-index

    1 publications

    126 citations

  7. Biologie cellulaire et Cancer

    Paris, France

    1 h-index

    1 publications

    72 citations

  8. Beijing University of Chemical Technology

    Beijing, China

    1 h-index

    1 publications

    79 citations

1–8 of 24

Venues

  1. Chemistry - A European Journal

    2 publications · 118 citations

    2

    h-index

  2. Biotechnology and Bioengineering

    1 publications · 63 citations

    1

    h-index

  3. Applied and Environmental Microbiology

    AEM · 1 publications · 14 citations

    1

    h-index

  4. Journal of Biological Chemistry

    JBC · 1 publications · 18 citations

    1

    h-index

  5. PubMed

    Repository · 1 publications · 17 citations

    1

    h-index

1–5