Concepedia

Enhancer Engineering

Enhancer Engineering is a molecular biology methodology that involves the targeted design and modification of cis-regulatory DNA sequences to precisely modulate the spatial, temporal, and quantitative aspects of gene expression in a programmable manner.

177

Publications

21.6K

Citations

1.3K

Authors

324

Institutions

Publications per year

2017–2026

43

Parents

Publications

177

Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations

Charles P. Fulco, Joseph Nasser, Thouis R. Jones et al. · Nature Genetics · 2019 · 1.2K citations · Full text

, , +16

In vivo enhancer analysis of human conserved non-coding sequences

L Pennacchio, Nadav Ahituv, Alan M Moses et al. · Nature · 2006 · 1.2K citations · Full text

, , +11

The Protein CTCF Is Required for the Enhancer Blocking Activity of Vertebrate Insulators

Adam C. Bell, Adam G. West, Gary Felsenfeld · Cell · 1999 · 1.1K citations · Full text

, , +15

Tools for neuroanatomy and neurogenetics in <i>Drosophila</i>

Barret D. Pfeiffer, Arnim Jenett, Ann S. Hammonds et al. · Proceedings of the National Academy of Sciences · 2008 · 1.1K citations · Full text

, , +17

BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis

Matthew C. Canver, Elenoe C. Smith, Falak Sher et al. · Nature · 2015 · 910 citations

, , +11

1–5 of 177

Authors

1.3K

  1. LP
    L Pennacchio

    Lawrence Berkeley National Laboratory, United States

    7 publications · 2.6K citations

    7

    h-index

  2. VA
    Veena Afzal

    Lawrence Berkeley National Laboratory, United States

    6 publications · 2.2K citations

    6

    h-index

  3. MP
    Michaela Pagani

    Research Institute of Molecular Pathology, Austria

    6 publications · 1K citations

    6

    h-index

  4. AS
    Alexander Stark

    Research Institute of Molecular Pathology, Austria

    6 publications · 1K citations

    6

    h-index

  5. IP
    Ingrid Plajzer-Frick

    Lawrence Berkeley National Laboratory, United States

    5 publications · 1.6K citations

    5

    h-index

1–5 of 1.3K

Institutions

324

  1. Lawrence Berkeley National Laboratory

    Berkeley, United States

    10 h-index

    74 publications

    31.6K citations

  2. Harvard University

    Cambridge, United States

    9 h-index

    64 publications

    15.6K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    9 h-index

    40 publications

    19.7K citations

  4. University of California, Berkeley

    Berkeley, United States

    9 h-index

    28 publications

    6.1K citations

  5. National Institutes of Health

    Bethesda, United States

    8 h-index

    21 publications

    5.4K citations

  6. Vienna Biocenter

    Vienna, Austria

    8 h-index

    33 publications

    6.8K citations

  7. Research Institute of Molecular Pathology

    Vienna, Austria

    8 h-index

    36 publications

    7K citations

  8. University of California, San Francisco

    San Francisco, United States

    7 h-index

    27 publications

    7.9K citations

1–8 of 324

Venues

  1. Biochemical and Biophysical Research Communications

    BBRC · 8 publications · 459 citations

    8

    h-index

  2. Nature

    6 publications · 2.8K citations

    6

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 2.1K citations

    6

    h-index

  4. Cell

    6 publications · 1.9K citations

    6

    h-index

  5. Nature Genetics

    5 publications · 2.1K citations

    5

    h-index

1–5