Concepedia

Regulatory Element Engineering

Regulatory Element Engineering is a subfield of genome engineering that focuses on the rational design, modification, and functional optimization of cis- and trans-acting regulatory DNA or RNA elements to achieve precise control of gene expression and gene regulatory network behavior in living systems.

248

Publications

23.6K

Citations

1.4K

Authors

415

Institutions

Publications per year

2017–2026

66

Parents

Children

Publications

248

Evolutionary changes in cis and trans gene regulation

Patricia J. Wittkopp, Belinda K. Haerum, Andrew G. Clark · Nature · 2004 · 958 citations

, , +14

Toehold Switches: De-Novo-Designed Regulators of Gene Expression

Alexander A. Green, Pamela A. Silver, James J. Collins et al. · Cell · 2014 · 841 citations · Full text

, , +16

Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription

Feng Zhang, Le Cong, Simona Lodato et al. · Nature Biotechnology · 2011 · 765 citations · Full text

, , +11

Analysis of P transposable element functions in drosophila

Roger E. Karess, Gerald M. Rubin · Cell · 1984 · 729 citations

, , +11

Spl elements protect a CpG island from de novo methylation

Michael Brandeis, Dale Frank, Iiana Keshet et al. · Nature · 1994 · 703 citations

, , +13

1–5 of 248

Authors

1.4K

  1. NA
    Nadav Ahituv

    University of California, San Francisco, United States

    5 publications · 583 citations

    5

    h-index

  2. PG
    Pavel Georgiev

    Institute of Gene Biology, Russia

    5 publications · 106 citations

    5

    h-index

  3. JD
    Jef D. Boeke

    Johns Hopkins University, United States

    4 publications · 188 citations

    4

    h-index

  4. HS
    Hal S. Alper

    The University of Texas at Austin, United States

    4 publications · 516 citations

    4

    h-index

  5. SK
    Sriram Kosuri

    University of California, Los Angeles, United States

    3 publications · 1.3K citations

    3

    h-index

1–5 of 1.4K

Institutions

415

  1. Harvard University

    Cambridge, United States

    14 h-index

    60 publications

    22.9K citations

  2. University of California, Berkeley

    Berkeley, United States

    11 h-index

    29 publications

    8.9K citations

  3. Chinese Academy of Sciences

    Beijing, China

    11 h-index

    70 publications

    7.2K citations

  4. Massachusetts Institute of Technology

    Cambridge, United States

    10 h-index

    30 publications

    10.6K citations

  5. University of California, San Francisco

    San Francisco, United States

    10 h-index

    42 publications

    5.9K citations

  6. Broad Institute

    Cambridge, United States

    8 h-index

    32 publications

    9.1K citations

  7. University of Washington

    Seattle, United States

    7 h-index

    16 publications

    3.6K citations

  8. Howard Hughes Medical Institute

    Chevy Chase, United States

    7 h-index

    13 publications

    1.7K citations

1–8 of 415

Venues

  1. Nucleic Acids Research

    12 publications · 1.3K citations

    11

    h-index

  2. Molecular and General Genetics MGG

    11 publications · 638 citations

    10

    h-index

  3. Methods in molecular biology

    Book series · 10 publications · 212 citations

    10

    h-index

  4. ACS Synthetic Biology

    10 publications · 496 citations

    10

    h-index

  5. Nature Communications

    7 publications · 678 citations

    7

    h-index

1–5