Concepedia

Conditional Gene Expression

Conditional Gene Expression is a genetic regulatory strategy that enables the spatial, temporal, or stimulus-dependent activation or repression of transgenes in engineered organisms, distinguished from constitutive expression by its reliance on engineered regulatory elements responsive to specific internal or external cues.

524

Publications

45.6K

Citations

3.1K

Authors

785

Institutions

Publications per year

2017–2026

79

Variants

Inducible Gene Expression

Parents

Publications

524

Conditional gene targeting in macrophages and granulocytes using LysMcre mice

Björn E. Clausen, Christoph Burkhardt, Walter Reith et al. · Transgenic Research · 1999 · 2.2K citations

, , +10

Analysis of lung tumor initiation and progression using conditional expression of oncogenic <i>K-ras</i>

Erica L. Jackson, Nicholas A. Willis, Kim L. Mercer et al. · Genes & Development · 2001 · 2K citations · Full text

, , +17

A conditional knockout resource for the genome-wide study of mouse gene function

William C. Skarnes, Barry P. Rosen, Anthony P. West et al. · Nature · 2011 · 1.8K citations

, , +16

A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei

Elizabeth Wirtz, Simone Leal, Claudia M. Ochatt et al. · Molecular and Biochemical Parasitology · 1999 · 1.5K citations

, , +17

A conditional tissue-specific transgene expression system using inducible GAL4

Thomas Osterwalder, Kenneth S. Yoon, Benjamin H. White et al. · Proceedings of the National Academy of Sciences · 2001 · 812 citations · Full text

, , +17

1–5 of 524

Authors

3.1K

  1. BS
    Beatrix Suess

    Technische Universität Darmstadt, Germany

    6 publications · 602 citations

    6

    h-index

  2. RK
    R Klemenz

    University Hospital of Zurich, Switzerland

    5 publications · 328 citations

    5

    h-index

  3. JD
    Jeffery D. Molkentin

    Cincinnati Children's Hospital Medical Center, United States

    5 publications · 386 citations

    5

    h-index

  4. HB
    Hermann Bujard

    Heidelberg University, Germany

    5 publications · 382 citations

    5

    h-index

  5. JW
    Jay W. Tichelaar

    Cincinnati Children's Hospital Medical Center, United States

    4 publications · 383 citations

    4

    h-index

1–5 of 3.1K

Institutions

785

  1. Heidelberg University

    Heidelberg, Germany

    16 h-index

    56 publications

    3.1K citations

  2. Harvard University

    Cambridge, United States

    13 h-index

    36 publications

    5.1K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    13 h-index

    49 publications

    20.4K citations

  4. Inserm

    Paris, France

    13 h-index

    51 publications

    1.6K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    13 h-index

    49 publications

    2.4K citations

  6. National Institutes of Health

    Bethesda, United States

    11 h-index

    24 publications

    2K citations

  7. University of Pennsylvania

    Philadelphia, United States

    10 h-index

    21 publications

    2.4K citations

  8. Cincinnati Children's Hospital Medical Center

    Cincinnati, United States

    10 h-index

    55 publications

    4.1K citations

1–8 of 785

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 42 publications · 7.2K citations

    38

    h-index

  2. PLoS ONE

    21 publications · 709 citations

    17

    h-index

  3. Nucleic Acids Research

    19 publications · 1.5K citations

    17

    h-index

  4. Molecular and Cellular Biology

    MCB · 17 publications · 1.1K citations

    16

    h-index

  5. genesis

    17 publications · 1.1K citations

    14

    h-index

1–5