Conditional gene targeting in macrophages and granulocytes using LysMcre mice

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

Federica Sallusto, Antonio Lanzavecchia · The Journal of Experimental Medicine · 1994 · 5.2K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor.

Kensuke Inaba, Muneo Inaba, Nikolaus Romani et al. · The Journal of Experimental Medicine · 1992 · 3.8K citations · Full text

Life Sciences, Cell Biology, Immunology +12

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

Kirk R. Thomas, Mario R. Capecchi · Cell · 1987 · 2.4K citations

Life Sciences, Developmental Biology, Molecular Biology +12

Inducible Gene Targeting in Mice

Ralf Kühn, Frieder Schwenk, Michel Aguet et al. · Science · 1995 · 1.9K citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Deletion of a DNA Polymerase β Gene Segment in T Cells Using Cell Type-Specific Gene Targeting

Hua Gu, Jamey D. Marth, Paul C. Orban et al. · Science · 1994 · 1.4K citations

Life Sciences, Genetics, Molecular Genetics +17