Matthew C. Canver

BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis

Matthew C. Canver, Elenoe C. Smith, Falak Sher et al. · Nature · 2015 · 910 citations

Life Sciences, Genetics, Molecular Genetics +11

An Erythroid Enhancer of <i>BCL11A</i> Subject to Genetic Variation Determines Fetal Hemoglobin Level

Daniel E. Bauer, Sophia C. Kamran, Samuel Lessard et al. · Science · 2013 · 667 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin

Takeshi Masuda, Xin Wang, Manami Maeda et al. · Science · 2016 · 378 citations

Medicine, Genetics, Hematology +12

Characterization of Genomic Deletion Efficiency Mediated by Clustered Regularly Interspaced Palindromic Repeats (CRISPR)/Cas9 Nuclease System in Mammalian Cells*

Matthew C. Canver, Daniel E. Bauer, Abhishek Dass et al. · Journal of Biological Chemistry · 2014 · 370 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype

Christian Brendel, Swaroopa Guda, Raffaele Renella et al. · Journal of Clinical Investigation · 2016 · 161 citations · Full text

Life Sciences, Genetics, Hematology +15