Samuel Lessard

An Erythroid Enhancer of <i>BCL11A</i> Subject to Genetic Variation Determines Fetal Hemoglobin Level

Daniel E. Bauer, Sophia C. Kamran, Samuel Lessard et al. · Science · 2013 · 645 citations · Full text

Bcl11a Expression, Lymphocyte Development, Genetics +19

Comparison of DNA methylation profiles in human fetal and adult red blood cell progenitors

Samuel Lessard, Mélissa Beaudoin, Karim Benkirane et al. · Genome Medicine · 2015 · 217 citations · Full text

Chromatin, Developmental Biology, Medicine +12

Human genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated loci

Samuel Lessard, Laurent C. Francioli, Jessica Alföldi et al. · Proceedings of the National Academy of Sciences · 2017 · 117 citations · Full text

Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci

Matthew C. Canver, Samuel Lessard, Luca Pinello et al. · Nature Genetics · 2017 · 116 citations · Full text

Genetic Analysis, Allelic Variant, Genetics +10

Genetic Risk Factors Associated With Preeclampsia and Hypertensive Disorders of Pregnancy

Jaakko Tyrmi, Tea Kaartokallio, A. Inkeri Lokki et al. · JAMA Cardiology · 2023 · 114 citations · Full text