Luca Pinello

BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis

Matthew C. Canver, Elenoe C. Smith, Falak Sher et al. · Nature · 2015 · 890 citations

Natural Sciences, Bcl11a Enhancer Dissection, Molecular Biology +6

Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing

Benjamin P. Kleinstiver, Alexander A. Sousa, Russell T. Walton et al. · Nature Biotechnology · 2019 · 690 citations

Base Editing, Engineered Crispr–cas12a Variants, Engineering +12

An Erythroid Enhancer of <i>BCL11A</i> Subject to Genetic Variation Determines Fetal Hemoglobin Level

Daniel E. Bauer, Sophia C. Kamran, Samuel Lessard et al. · Science · 2013 · 645 citations · Full text

Bcl11a Expression, Lymphocyte Development, Genetics +19

Highly efficient therapeutic gene editing of human hematopoietic stem cells

Yuxuan Wu, Jing Zeng, Benjamin P. Roscoe et al. · Nature Medicine · 2019 · 504 citations

Induced Pluripotent Stem Cell, Genome Surgery, Medicine +7

LincRNA-p21 Regulates Neointima Formation, Vascular Smooth Muscle Cell Proliferation, Apoptosis, and Atherosclerosis by Enhancing p53 Activity

Gengze Wu, Jin Cai, Yu Han et al. · Circulation · 2014 · 479 citations · Full text