Expanded encyclopaedias of DNA elements in the human and mouse genomes

Federico Abascal, Reyes Acosta, Nicholas J. Addleman, +530

Nature

In vivo enhancer analysis of human conserved non-coding sequences

L Pennacchio, Nadav Ahituv, Alan M Moses, +16

Nature

Transcriptional RegulationGeneticsVivo Enhancer AnalysisGene CharacterizationGene Expression +2

Enhancer redundancy provides phenotypic robustness in mammalian development

Marco Osterwalder, Iros Barozzi, Virginie Tissières, +17

Nature

Developmental BiologyGeneticsEnhancer RedundancyGenomic MechanismGenetic Mechanism +3

Scanning Human Gene Deserts for Long-Range Enhancers

Marcelo A. Nóbrega, Ivan Ovcharenko, Veena Afzal, +1

Science

AltmetricsFunctional GenomicsEngineeringData ScienceMeasurement +12

An atlas of dynamic chromatin landscapes in mouse fetal development

David U. Gorkin, Iros Barozzi, Yuan Zhao, +39

Nature

Rapid and Pervasive Changes in Genome-wide Enhancer Usage during Mammalian Development

Alex S. Nord, Matthew J. Blow, Catia Attanasio, +11

Cell

Knockout MouseDevelopmental BiologyMedicineGeneticsGenomic Mechanism +4

Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation

Rongxin Fang, Hui Huang, Yuan Zhao, +11

Nature Neuroscience

ChromatinTranscriptional RegulationDevelopmental BiologyChromatin StructureChromatin Remodeling +10

Human-Specific Gain of Function in a Developmental Enhancer

Shyam Prabhakar, Axel Visel, Jennifer A. Akiyama, +10

Science

Progressive Loss of Function in a Limb Enhancer during Snake Evolution

Evgeny Z. Kvon, Olga K. Kamneva, Uirá Souto Melo, +16

Cell

BiologyDevelopmental BiologyProgressive LossMedicineNatural Sciences +10

Deletion of Ultraconserved Elements Yields Viable Mice

Nadav Ahituv, Yiwen Zhu, Axel Visel, +4

PLoS Biology

Knockout MouseXenotransplantationDevelopmental BiologyEssential Functional PropertiesGenetics +11