Concepedia

Dose-dependent Interaction Effects

Dose-Dependent Interaction Effects is a pharmacokinetic phenomenon in drug-drug interactions affecting bioavailability wherein the magnitude of the interaction varies as a function of the administered dose of one or both interacting drugs.

126

Publications

13.6K

Citations

639

Authors

246

Institutions

Publications per year

2017–2026

28

Parents

Publications

126

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

Ting‐Chao Chou, Paul Talalay · Advances in Enzyme Regulation · 1984 · 7.2K citations

, , +16

Analysis of combined drug effects: a new look at a very old problem

Ting‐Chao Chou, Paul Talalay · Trends in Pharmacological Sciences · 1983 · 623 citations

, , +5

Gilbert syndrome and glucose-6-phosphate dehydrogenase deficiency: A dose-dependent genetic interaction crucial to neonatal hyperbilirubinemia

Michael Kaplan, Paul Renbaum, Ephrat Levy‐Lahad et al. · Proceedings of the National Academy of Sciences · 1997 · 347 citations

, , +17

Influenza and COPD Mortality Protection as Pleiotropic, Dose-Dependent Effects of Statins

Floyd J. Frost, Hans Petersen, Kristine Tollestrup et al. · CHEST Journal · 2007 · 303 citations

, , +12

Dose-Dependent Interaction of Tbx1 and Crkl and Locally Aberrant RA Signaling in a Model of del22q11 Syndrome

Deborah L. Guris, Gregg Duester, Virginia E. Papaioannou et al. · Developmental Cell · 2006 · 212 citations · Full text

, , +7

1–5 of 126

Authors

639

  1. TC
    Ting‐Chao Chou

    Memorial Sloan Kettering Cancer Center, United States

    2 publications · 7.8K citations

    2

    h-index

  2. SK
    Sunao Kaneko

    Hirosaki University, Japan

    2 publications · 65 citations

    2

    h-index

  3. PT
    Paul Talalay

    Johns Hopkins University, United States

    2 publications · 7.8K citations

    2

    h-index

  4. NY
    Norio Yasui‐Furukori

    Hirosaki University, Japan

    2 publications · 65 citations

    2

    h-index

  5. FK
    Frank König

    Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Germany

    1 publications · 27 citations

    1

    h-index

1–5 of 639

Institutions

246

  1. Harvard University

    Cambridge, United States

    3 h-index

    7 publications

    670 citations

  2. Charité - Universitätsmedizin Berlin

    Berlin, Germany

    3 h-index

    22 publications

    521 citations

  3. State Key Laboratory of Food Science and Technology

    Wuxi, China

    3 h-index

    18 publications

    414 citations

  4. Memorial Sloan Kettering Cancer Center

    New York, United States

    3 h-index

    3 publications

    7.9K citations

  5. Hirosaki University

    Hirosaki, Japan

    3 h-index

    10 publications

    352 citations

  6. Johns Hopkins University

    Baltimore, United States

    3 h-index

    5 publications

    7.9K citations

  7. University of Colorado Denver

    Denver, United States

    3 h-index

    14 publications

    308 citations

  8. Jiangnan University

    Wuxi, China

    3 h-index

    14 publications

    304 citations

1–8 of 246

Venues

  1. PubMed

    Repository · 8 publications · 280 citations

    8

    h-index

  2. PLoS ONE

    3 publications · 122 citations

    3

    h-index

  3. Chemosphere

    3 publications · 106 citations

    3

    h-index

  4. Human & Experimental Toxicology

    2 publications · 38 citations

    2

    h-index

  5. Psychopharmacology

    2 publications · 64 citations

    2

    h-index

1–5