Concepedia

Differentiation-associated Epigenetic Changes

Differentiation-Associated Epigenetic Changes is a biological phenomenon within epigenetic reprogramming that refers to the systematic alterations in epigenetic marks—such as DNA methylation and histone modifications—occurring in a cell lineage-specific manner during cellular differentiation, thereby establishing and maintaining distinct gene expression profiles necessary for specialized cell function.

196

Publications

16.7K

Citations

1.4K

Authors

494

Institutions

Publications per year

2017–2026

56

Parents

Publications

196

IDH mutation impairs histone demethylation and results in a block to cell differentiation

Chao Lü, Patrick S. Ward, Gurpreet S. Kapoor et al. · Nature · 2012 · 2K citations

, , +14

Cellular differentiation, cytidine analogs and DNA methylation

Peter A. Jones, Shirley M. Taylor · Cell · 1980 · 1.9K citations

, , +16

TH cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes

Orly Avni, Dong Hun Lee, Fernando Macián et al. · Nature Immunology · 2002 · 523 citations

, , +16

Recurrent Variations in DNA Methylation in Human Pluripotent Stem Cells and Their Differentiated Derivatives

Kristopher L. Nazor, Gülşah Altun, C. Lynch et al. · Cell stem cell · 2012 · 425 citations · Full text

, , +17

DNA Methylation Dynamics during In Vivo Differentiation of Blood and Skin Stem Cells

Christoph Bock, Isabel Beerman, Wen‐Hui Lien et al. · Molecular Cell · 2012 · 411 citations · Full text

, , +16

1–5 of 196

Authors

1.4K

  1. RN
    Rūta Navakauskienė

    Vilnius University, Lithuania

    4 publications · 131 citations

    4

    h-index

  2. KZ
    Keji Zhao

    National Heart Lung and Blood Institute, United States

    3 publications · 205 citations

    3

    h-index

  3. WL
    Wiesława Leśniak

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego, Poland

    3 publications · 46 citations

    3

    h-index

  4. HB
    Hossein Baharvand

    Royan Institute, Iran

    3 publications · 71 citations

    3

    h-index

  5. MS
    Maryam Shahhoseini

    Royan Institute, Iran

    3 publications · 53 citations

    3

    h-index

1–5 of 1.4K

Institutions

494

  1. Harvard University

    Cambridge, United States

    12 h-index

    54 publications

    10.6K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    22 publications

    1.4K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    6 h-index

    11 publications

    1.4K citations

  4. Inserm

    Paris, France

    5 h-index

    34 publications

    1.6K citations

  5. University of Cambridge

    Cambridge, United Kingdom

    5 h-index

    17 publications

    2.4K citations

  6. Dana-Farber Cancer Institute

    Boston, United States

    5 h-index

    16 publications

    3.1K citations

  7. Stanford University

    Stanford, United States

    4 h-index

    23 publications

    4.8K citations

  8. Royan Institute

    Tehran, Iran

    4 h-index

    15 publications

    339 citations

1–8 of 494

Venues

  1. PLoS ONE

    12 publications · 338 citations

    11

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 8 publications · 796 citations

    8

    h-index

  3. Nucleic Acids Research

    6 publications · 382 citations

    6

    h-index

  4. Molecular and Cellular Biology

    MCB · 6 publications · 600 citations

    6

    h-index

  5. Scientific Reports

    6 publications · 194 citations

    6

    h-index

1–5