Concepedia

Clonal Dynamics

Clonal Dynamics is the study of the temporal evolution and competitive interactions among genetically distinct subpopulations of cells within a tumor, characterized by the expansion, contraction, or stabilization of specific clones driven by somatic mutations and selective pressures in the context of cancer progression and treatment.

867

Publications

95.6K

Citations

5.7K

Authors

1.5K

Institutions

Publications per year

2017–2026

288

Parents

Children

Publications

867

The Clonal Evolution of Tumor Cell Populations

Peter C. Nowell̀ · Science · 1976 · 6.5K citations

, , +17

Tracking the Evolution of Non–Small-Cell Lung Cancer

Mariam Jamal‐Hanjani, Gareth A. Wilson, Nicholas McGranahan et al. · New England Journal of Medicine · 2017 · 2.4K citations · Full text

, , +17

The clonal and mutational evolution spectrum of primary triple-negative breast cancers

Sohrab P. Shah, Andrew Roth, Rodrigo Goya et al. · Nature · 2012 · 2K citations

, , +14

Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer

Himisha Beltran, Davide Prandi, Juan Miguel Mosquera et al. · Nature Medicine · 2016 · 1.7K citations · Full text

, , +14

Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia

Dan A. Landau, Scott L. Carter, Petar Stojanov et al. · Cell · 2013 · 1.4K citations · Full text

, , +14

1–5 of 867

Authors

5.7K

  1. RA
    Robert A. Gatenby

    Moffitt Cancer Center, United States

    19 publications · 2.6K citations

    15

    h-index

  2. BW
    Benjamin Werner

    Institute of Cancer Research, United Kingdom

    14 publications · 1.8K citations

    14

    h-index

  3. FM
    Franziska Michor

    Dana-Farber Cancer Institute, United States

    14 publications · 4.3K citations

    14

    h-index

  4. TA
    Trevor A. Graham

    Queen Mary University of London, United Kingdom

    15 publications · 1.8K citations

    14

    h-index

  5. AS
    Andrea Sottoriva

    Institute of Cancer Research, United Kingdom

    16 publications · 2.1K citations

    14

    h-index

1–5 of 5.7K

Institutions

1.5K

  1. Harvard University

    Cambridge, United States

    39 h-index

    208 publications

    39.7K citations

  2. Dana-Farber Cancer Institute

    Boston, United States

    28 h-index

    182 publications

    53.4K citations

  3. Heidelberg University

    Heidelberg, Germany

    27 h-index

    122 publications

    8.2K citations

  4. University of Cambridge

    Cambridge, United Kingdom

    25 h-index

    133 publications

    32.4K citations

  5. The University of Texas MD Anderson Cancer Center

    Houston, United States

    25 h-index

    258 publications

    54.4K citations

  6. University College London

    London, United Kingdom

    23 h-index

    187 publications

    223K citations

  7. Institute of Cancer Research

    London, United Kingdom

    21 h-index

    177 publications

    33.5K citations

  8. Moffitt Cancer Center

    Tampa, United States

    21 h-index

    110 publications

    13.3K citations

1–8 of 1.5K

Venues

  1. Blood

    57 publications · 6.6K citations

    40

    h-index

  2. Nature

    35 publications · 13.7K citations

    34

    h-index

  3. Nature Communications

    39 publications · 4.8K citations

    33

    h-index

  4. PubMed

    Repository · 40 publications · 3.8K citations

    26

    h-index

  5. Leukemia

    28 publications · 2.2K citations

    23

    h-index

1–5