Metastatic Clonal Evolution is a theoretical framework in cancer biology that describes the process by which distinct subclones of tumor cells evolve through genetic and epigenetic alterations during the progression and spread of cancer to distant organs, thereby accounting for heterogeneity and adaptation in metastatic disease.
107
Publications
15.4K
Citations
1.3K
Authors
436
Institutions
Publications per year
2017–2026
45
Parents
Publications
107
Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer
Himisha Beltran, Davide Prandi, Juan Miguel Mosquera et al. · Nature Medicine · 2016 · 1.7K citations · Full text
The evolutionary history of lethal metastatic prostate cancer
Gunes Gundem, Peter Van Loo, Bárbara Kremeyer et al. · Nature · 2015 · 1.4K citations · Full text
Metastasis Results from Preexisting Variant Cells Within a Malignant Tumor
Isaiah J. Fidler, Margaret L. Kripke · Science · 1977 · 1.4K citations
Medicine, Cancer Biology, Oncology +17
Biological Diversity in Metastatic Neoplasms: Origins and Implications
Isaiah J. Fidler, Ian R. Hart · Science · 1982 · 935 citations
Medicine, Cancer Biology, Oncology +17
Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal
Samra Turajlic, Hang Xu, Kevin Litchfield et al. · Cell · 2018 · 875 citations · Full text
Medicine, Cancer Biology, Oncology +17
1–5 of 107
Authors
1.3K
- IJIsaiah J. Fidler
The University of Texas MD Anderson Cancer Center, United States
4 publications · 3K citations
4
h-index
- RS
3
h-index
- JF
3
h-index
- GLGarth L. Nicolson
The University of Texas MD Anderson Cancer Center, United States
3 publications · 347 citations
3
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- EPElli Papaemmanuil
Memorial Sloan Kettering Cancer Center, United States
3 publications · 1.6K citations
3
h-index
1–5 of 1.3K
Institutions
436
National Institutes of Health
Bethesda, United States
8 h-index
12 publications
4.8K citations
The University of Texas MD Anderson Cancer Center
Houston, United States
7 h-index
75 publications
4.9K citations
Memorial Sloan Kettering Cancer Center
New York, United States
6 h-index
41 publications
5.3K citations
Ontario Institute for Cancer Research
Toronto, Canada
5 h-index
6 publications
637 citations
Inserm
Paris, France
5 h-index
30 publications
1.3K citations
University of Toronto
Toronto, Canada
5 h-index
16 publications
4.2K citations
Heidelberg University
Heidelberg, Germany
5 h-index
26 publications
5.1K citations
Centre for Cancer Biology
Adelaide, Australia
4 h-index
4 publications
658 citations
1–8 of 436
Venues
- PubMed
Repository · 13 publications · 1.2K citations
12
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- Proceedings of the National Academy of Sciences
PNAS · 8 publications · 2.1K citations
8
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- Nature Communications
6 publications · 698 citations
6
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- International Journal of Cancer
6 publications · 330 citations
6
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- Clinical & Experimental Metastasis
5 publications · 353 citations
5
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