Cellular Oxygen Sensitivity

Cellular Oxygen Sensitivity is a biological construct that characterizes the degree to which cellular responses to ionizing radiation are modulated by the presence or concentration of molecular oxygen, distinguishing it from other radiobiological parameters by its specific dependence on oxygen-mediated radical formation in determining radiosensitivity.

448

Publications

32.2K

Citations

1.4K

Authors

408

Institutions

Publications per year

2017–2026

Parents

Oxygen Effect

Publications

448

Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O <sub>2</sub> -Regulated Prolyl Hydroxylation

Panu Jaakkola, David R. Mole, Ya‐Min Tian et al. · Science · 2001 · 5.5K citations

Life Sciences, Biochemistry, Molecular Biology +17

The Concentration of Oxygen Dissolved in Tissues at the Time of Irradiation as a Factor in Radiotherapy

L. H. Gray, Alan D. Conger, M. Ebert et al. · British Journal of Radiology · 1953 · 2.2K citations

Medicine, Cancer Biology, Oncology +14

Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

Simona Parrinello, Enrique Samper, Ana Krtolica et al. · Nature Cell Biology · 2003 · 1.1K citations · Full text

Education, Biochemistry, Cell Biology +13

II. Clinical Application

I. Churchill‐Davidson, Cyril Sanger, R. H. Thomlinson · British Journal of Radiology · 1957 · 612 citations

Medicine, Oncology, Radiation Oncology +13

A Human-Like Senescence-Associated Secretory Phenotype Is Conserved in Mouse Cells Dependent on Physiological Oxygen

Jean-Philippe Coppé, Christopher K. Patil, Françis Rodier et al. · PLoS ONE · 2010 · 446 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

1–5 of 448

Authors

1.4K

ER
Edward R. Epp
Massachusetts General Hospital, United States
11 publications · 740 citations
10
h-index
TA
Tikvah Alper
Hammersmith Hospital, United Kingdom
10 publications · 868 citations
10
h-index
CC
C. Clifton Ling
George Washington University, United States
8 publications · 354 citations
8
h-index
CJ
C. J. Koch
University of Pennsylvania, United States
7 publications · 307 citations
7
h-index
RE
Ralph E. Durand
Occupational Cancer Research Centre, Canada
7 publications · 282 citations
7
h-index

1–5 of 1.4K

Institutions

408

1–8 of 408

Venues

Radiation Research
75 publications · 3.8K citations
34
h-index
PubMed
Repository · 35 publications · 1.8K citations
22
h-index
British Journal of Radiology
BJR · 22 publications · 3.8K citations
19
h-index
International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine
28 publications · 755 citations
17
h-index
Nature
19 publications · 1.4K citations
16
h-index

1–5