Concepedia

Cell Type-specific Silencing

Cell Type-Specific Silencing is a regulatory mechanism in gene expression control whereby silencer elements selectively repress transcription in particular cell types while remaining inactive in others, thereby ensuring precise spatial and functional specificity in genomic regulation.

102

Publications

6.2K

Citations

628

Authors

238

Institutions

Publications per year

2017–2026

32

Parents

Publications

102

Induction of the interferon response by siRNA is cell type– and duplex length–dependent

Angela Reynolds, Emily M. Anderson, Annaleen Vermeulen et al. · RNA · 2006 · 317 citations · Full text

, , +17

Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts

Donna Nofziger, Alison Miyamoto, Karen M. Lyons et al. · Development · 1999 · 293 citations

, , +14

Systematic identification of silencers in human cells

Baoxu Pang, M Snyder · Nature Genetics · 2020 · 201 citations · Full text

, , +7

A cell type-preferred silencer element that controls the neural-specific expression of the SCG10 gene

Nozomu Mori, Reuven Stein, O Sigmund et al. · Neuron · 1990 · 190 citations

, , +14

Mice doubly deficient for the Polycomb Group genes <i>Mel18</i> and <i>Bmi1</i> reveal synergy and requirement for maintenance but not initiation of Hox gene expression

Takeshi Akasaka, Maarten van Lohuizen, Nathalie van der Lugt et al. · Development · 2001 · 189 citations

, , +13

1–5 of 102

Authors

628

  1. JQ
    Jing Qu

    Chinese Academy of Sciences, China

    2 publications · 121 citations

    2

    h-index

  2. RH
    Ruben H. Hovhannisyan

    University of Pennsylvania, United States

    2 publications · 57 citations

    2

    h-index

  3. PC
    Piu Chan

    Capital Medical University, China

    2 publications · 121 citations

    2

    h-index

  4. NR
    Natacha Raich

    Inserm, France

    2 publications · 132 citations

    2

    h-index

  5. NM
    Nozomu Mori

    Kagawa University, Japan

    2 publications · 212 citations

    2

    h-index

1–5 of 628

Institutions

238

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    6 h-index

    18 publications

    2.5K citations

  2. University of Pennsylvania

    Philadelphia, United States

    5 h-index

    14 publications

    856 citations

  3. National Institutes of Health

    Bethesda, United States

    5 h-index

    14 publications

    403 citations

  4. Harvard University

    Cambridge, United States

    4 h-index

    15 publications

    1.5K citations

  5. Chinese Academy of Sciences

    Beijing, China

    4 h-index

    27 publications

    1.3K citations

  6. Memorial Sloan Kettering Cancer Center

    New York, United States

    3 h-index

    18 publications

    2.3K citations

  7. University of Chinese Academy of Sciences

    Beijing, China

    3 h-index

    29 publications

    1.4K citations

  8. Inserm

    Paris, France

    2 h-index

    15 publications

    641 citations

1–8 of 238

Venues

  1. Journal of Biological Chemistry

    JBC · 8 publications · 363 citations

    8

    h-index

  2. PLoS ONE

    5 publications · 253 citations

    5

    h-index

  3. Nucleic Acids Research

    5 publications · 201 citations

    5

    h-index

  4. Nature Communications

    4 publications · 159 citations

    4

    h-index

  5. Molecular and Cellular Biology

    MCB · 4 publications · 254 citations

    4

    h-index

1–5