Concepedia

Biomarker Development

Biomarker Development is a translational research process that systematically identifies, analytically validates, and clinically qualifies biological characteristics as reliable indicators of disease states, therapeutic response, or safety, specifically for informing and de-risking gene therapy translation.

1.7K

Publications

97.7K

Citations

12.3K

Authors

3.2K

Institutions

Publications per year

2017–2026

708

Parents

Children

Publications

1.7K

Youden Index and Optimal Cut‐Point Estimated from Observations Affected by a Lower Limit of Detection

Marcus D. Ruopp, Neil J. Perkins, Brian W. Whitcomb et al. · Biometrical Journal · 2008 · 1.3K citations · Full text

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Cutoff Finder: A Comprehensive and Straightforward Web Application Enabling Rapid Biomarker Cutoff Optimization

Jan Budczies, Frederick Klauschen, Bruno V. Sinn et al. · PLoS ONE · 2012 · 1.3K citations · Full text

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Cancer biomarker detection: recent achievements and challenges

Li Wu, Xiaogang Qu · Chemical Society Reviews · 2015 · 1.2K citations

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Optimal Cut-point and Its Corresponding Youden Index to Discriminate Individuals Using Pooled Blood Samples

Enrique F. Schisterman, Neil J. Perkins, Aiyi Liu et al. · Epidemiology · 2004 · 1.2K citations

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Systems Biology and New Technologies Enable Predictive and Preventative Medicine

Leroy Hood, James R. Heath, Michael E. Phelps et al. · Science · 2004 · 1.1K citations

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1–5 of 1.7K

Authors

12.3K

  1. FG
    Fabio Garofolo

    Bristol-Myers Squibb (United States), United States

    12 publications · 516 citations

    12

    h-index

  2. NS
    Natasha Savoie

    United States Food and Drug Administration, United States

    11 publications · 418 citations

    11

    h-index

  3. YS
    Yoshiro Saito

    National Institute of Health Sciences, Japan

    11 publications · 395 citations

    11

    h-index

  4. AI
    Akiko Ishii‐Watabe

    National Institute of Health Sciences, Japan

    10 publications · 366 citations

    10

    h-index

  5. JP
    João Pedras-Vasconcelos

    Pfizer (United States), United States

    9 publications · 404 citations

    9

    h-index

1–5 of 12.3K

Institutions

3.2K

  1. Harvard University

    Cambridge, United States

    32 h-index

    138 publications

    11K citations

  2. National Cancer Institute

    Bethesda, United States

    31 h-index

    142 publications

    14K citations

  3. National Institutes of Health

    Bethesda, United States

    28 h-index

    134 publications

    13.9K citations

  4. University of Washington

    Seattle, United States

    27 h-index

    95 publications

    10.3K citations

  5. Pfizer (United States)

    New York, United States

    26 h-index

    105 publications

    8.5K citations

  6. United States Food and Drug Administration

    Silver Spring, United States

    26 h-index

    243 publications

    11K citations

  7. Fred Hutch Cancer Center

    Seattle, United States

    25 h-index

    106 publications

    11.5K citations

  8. Johns Hopkins University

    Baltimore, United States

    25 h-index

    123 publications

    5.6K citations

1–8 of 3.2K

Venues

  1. PLoS ONE

    57 publications · 5.3K citations

    30

    h-index

  2. PubMed

    Repository · 55 publications · 2.8K citations

    27

    h-index

  3. Scientific Reports

    26 publications · 1.2K citations

    20

    h-index

  4. Bioanalysis

    BIO · 30 publications · 1K citations

    20

    h-index

  5. Clinical Chemistry

    29 publications · 2K citations

    20

    h-index

1–5