Concepedia

Biomarker Cutoff Optimization

Biomarker Cutoff Optimization is the systematic process of determining the optimal threshold value for a biomarker’s measurement that maximally discriminates between clinically relevant states, such as disease presence or absence, by balancing sensitivity, specificity, and other performance metrics.

10

Publications

2.1K

Citations

57

Authors

29

Institutions

Publications per year

2017–2026

4

Parents

Publications

10

Cutoff Finder: A Comprehensive and Straightforward Web Application Enabling Rapid Biomarker Cutoff Optimization

Jan Budczies, Frederick Klauschen, Bruno V. Sinn et al. · PLoS ONE · 2012 · 1.3K citations · Full text

, , +17

Centiloid cut-off values for optimal agreement between PET and CSF core AD biomarkers

Gemma Salvadó, José Luís Molinuevo, Anna Brugulat‐Serrat et al. · Alzheimer s Research & Therapy · 2019 · 205 citations · Full text

, , +17

Evaluate Cutpoints: Adaptable continuous data distribution system for determining survival in Kaplan-Meier estimator

Magdalena Ogłuszka, Magdalena Orzechowska, Dorota Jędroszka et al. · Computer Methods and Programs in Biomedicine · 2019 · 192 citations · Full text

, , +17

Two-graph receiver operating characteristic (TG-ROC): update version supports optimisation of cut-off values that minimise overall misclassification costs

Matthias Greiner · Journal of Immunological Methods · 1996 · 125 citations

, , +9

Evaluating the effect of optimized cutoff values in the assessment of prognostic factors

Berthold Lausen, Martin Schumacher · Computational Statistics & Data Analysis · 1996 · 108 citations

, , +9

1–5 of 10

Authors

57

  1. BK
    Betsy Kristjansson

    University of Ottawa, Canada

    1 publications · 14 citations

    1

    h-index

  2. BG
    Balázs Győrffy

    Semmelweis University, Hungary

    1 publications · 1.3K citations

    1

    h-index

  3. MK
    Maciej Kostrubiec

    Medical University of Warsaw, Poland

    1 publications · 57 citations

    1

    h-index

  4. KB
    Kaj Blennow

    University of Gothenburg, Sweden

    1 publications · 205 citations

    1

    h-index

  5. JD
    Juan Domingo Gispert

    Pasqual Maragall Foundation, Spain

    1 publications · 205 citations

    1

    h-index

1–5 of 57

Institutions

29

  1. Instituto Ramón y Cajal de Investigación Sanitaria

    Madrid, Spain

    1 h-index

    1 publications

    57 citations

  2. University of Milano-Bicocca

    Milan, Italy

    1 h-index

    2 publications

    94 citations

  3. Medical University of Lodz

    Lodz, Poland

    1 h-index

    5 publications

    960 citations

  4. Hospital Clínic de Barcelona

    Barcelona, Spain

    1 h-index

    3 publications

    615 citations

  5. Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine

    Madrid, Spain

    1 h-index

    4 publications

    820 citations

  6. Sahlgrenska University Hospital

    Gothenburg, Sweden

    1 h-index

    3 publications

    615 citations

  7. Heidelberg University

    Heidelberg, Germany

    1 h-index

    1 publications

    57 citations

  8. University Medical Center of the Johannes Gutenberg University Mainz

    Mainz, Germany

    1 h-index

    4 publications

    228 citations

1–8 of 29

Venues

  1. Computational Statistics & Data Analysis

    CSDA · 2 publications · 155 citations

    2

    h-index

  2. Computer Methods and Programs in Biomedicine

    1 publications · 192 citations

    1

    h-index

  3. European Respiratory Journal

    1 publications · 57 citations

    1

    h-index

  4. Journal of Clinical Epidemiology

    1 publications · 14 citations

    1

    h-index

  5. Alzheimer s Research & Therapy

    1 publications · 205 citations

    1

    h-index

1–5