Concepedia

Apoptosis Threshold Control

Apoptosis Threshold Control is a regulatory framework in cell biology that determines the critical signaling threshold required to initiate programmed cell death, distinguishing it from passive cell death mechanisms by its dependence on precise molecular cues and feedback dynamics.

7

Publications

398

Citations

53

Authors

16

Institutions

Publications per year

2017–2026

1

Parents

Publications

7

MicroRNA-24 regulates XIAP to reduce the apoptosis threshold in cancer cells

Yi Xie, Lisa A. Tobin, Jordi Camps et al. · Oncogene · 2012 · 99 citations · Full text

, , +16

Apoptosis Threshold Set by Noxa and Mcl-1 after T Cell Activation Regulates Competitive Selection of High-Affinity Clones

Felix M. Wensveen, Klaas P. J. M. van Gisbergen, Ingrid A. M. Derks et al. · Immunity · 2010 · 91 citations · Full text

, , +12

Induction of apoptosis and chemosensitization of mesothelioma cells by Bcl‐2 and Bcl‐xL antisense treatment

Sally Hopkins‐Donaldson, Richard Cathomas, Ana Paula Simões‐Wüst et al. · International Journal of Cancer · 2003 · 70 citations

, , +17

A Comprehensive Systems Biological Study of Autophagy-Apoptosis Crosstalk during Endoplasmic Reticulum Stress

Marianna Holczer, Margita Márton, Anita Kurucz et al. · BioMed Research International · 2015 · 55 citations · Full text

, , +17

p63 uses a switch-like mechanism to set the threshold for induction of apoptosis

Jakob Gebel, Marcel Tuppi, A. Chaikuad et al. · Nature Chemical Biology · 2020 · 52 citations · Full text

, , +11

1–5 of 7

Authors

53

  1. RC
    Richard Cathomas

    Kantonsspital Graubünden, Switzerland

    1 publications · 70 citations

    1

    h-index

  2. DW
    Darawalee Wangsa

    National Cancer Institute, United States

    1 publications · 99 citations

    1

    h-index

  3. DC
    Dario C. Altieri

    The Wistar Institute, United States

    1 publications · 17 citations

    1

    h-index

  4. AC
    A. Chaikuad

    Goethe University Frankfurt, Germany

    1 publications · 52 citations

    1

    h-index

  5. EH
    Erik Henrich

    Goethe University Frankfurt, Germany

    1 publications · 52 citations

    1

    h-index

1–5 of 53

Institutions

16

  1. Swedish Chemicals Agency

    Sundbyberg, Sweden

    1 h-index

    1 publications

    99 citations

  2. Semmelweis University

    Budapest, Hungary

    1 h-index

    5 publications

    275 citations

  3. The Francis Crick Institute

    London, United Kingdom

    1 h-index

    1 publications

    52 citations

  4. The Netherlands Cancer Institute

    Amsterdam, The Netherlands

    1 h-index

    2 publications

    182 citations

  5. National Cancer Institute

    Bethesda, United States

    1 h-index

    11 publications

    1.1K citations

  6. National Institutes of Health

    Bethesda, United States

    1 h-index

    10 publications

    990 citations

  7. The Royal Free Hospital

    London, United Kingdom

    1 h-index

    3 publications

    42 citations

  8. Oncode Institute

    Utrecht, Netherlands

    1 h-index

    2 publications

    182 citations

1–8 of 16

Venues

  1. Nature Chemical Biology

    1 publications · 52 citations

    1

    h-index

  2. Cell Cycle

    1 publications · 17 citations

    1

    h-index

  3. BioMed Research International

    1 publications · 55 citations

    1

    h-index

  4. International Journal of Cancer

    1 publications · 70 citations

    1

    h-index

  5. Immunity

    1 publications · 91 citations

    1

    h-index

1–5